A contiguous high-resolution radiation hybrid map of 44 loci from the distal portion of the long arm of human chromosome 5.
A contiguous high-resolution radiation hybrid map of 44 loci from the distal portion of the long arm of human chromosome 5.
复制标题
人类 5 号染色体长臂远端 44 个基因座的连续高分辨率辐射杂交图谱。
DOI：
10.1101/gr.6.7.628
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发表时间：
1996
期刊：
影响因子：
7
通讯作者：
Wasmuth,JJ
中科院分区：
文献类型：
--
作者：
Warrington,JA;Wasmuth,JJ
使用辐射混合 (RH) 作图结合自然缺失作图面板，生成了来自人类 5 号染色体 q21-q35 长臂远端区域 35 Mb 部分的 44 个基因座的连续高分辨率图谱。该图谱包括 30 个基因、4 个序列标记位点 (STS) 基因座和 10 个 DNA 标记。新作图的标记填补了先前图谱中存在的标记 FER-IL4 和 IL3-IL9 之间的两个空白区域。确定基因在物理图谱上的位置有助于定位克隆工作，并有助于我们了解人类基因组的整体组织。
A contiguous high-resolution map of 44 loci from a 35-Mb portion of the distal region of the long arm of human chromosome 5, q21-q35, was produced using radiation hybrid (RH) mapping in conjunction with a natural deletion mapping panel. The map includes 30 genes, four sequence-tagged site (STS) loci, and 10 DNA markers. Newly mapped markers fill two gap regions that were present in previous maps, between markers FER-IL4 and IL3-IL9. Identifying the position of genes on the physical map aids in positional cloning efforts and contributes to our understanding of the overall organization of the human genome.