Using quantitative wastewater analysis to measure daily usage of conventional and emerging illicit drugs at an annual music festival
Using quantitative wastewater analysis to measure daily usage of conventional and emerging illicit drugs at an annual music festival
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DOI：
10.1111/dar.12061
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发表时间：
2013-11-01
影响因子：
3.8
通讯作者：
Mueller, Jochen F.
中科院分区：
文献类型：
--
作者：
Lai, Foon Yin;Thai, Phong K.;Mueller, Jochen F.
前言和目的废水分析提供了一种非侵入性的方法来测量人群中的药物使用情况。在连续两年（2010年和2011年）的年度音乐节上，我们使用这种方法来确定常规非法药物[大麻，可卡因，甲基苯丙胺和3,4-亚甲基二氧甲基苯丙胺（MDMA）]和新兴非法精神兴奋剂（苄哌嗪，甲氧麻黄酮和甲基酮）的日常使用情况。设计与方法从现场污水处理厂收集具有代表性的日常复合废水样本，分析药物代谢物。2年以上资料采用Wilcoxon配对检验进行比较。2010年节日的数据与同期从附近城市社区收集的数据使用等效方法进行了比较。结果所有样本均检出常规违禁药物，而新出现的违禁精神兴奋剂仅在特定日期检出。在这两个节日期间，MDMA、可卡因和大麻的估计人均消费量相似。统计学意义(P)
Introduction and AimsWastewater analysis provides a non-intrusive way of measuring drug use within a population. We used this approach to determine daily use of conventional illicit drugs [cannabis, cocaine, methamphetamine and 3,4-methylenedioxymethamphetamine (MDMA)] and emerging illicit psychostimulants (benzylpiperazine, mephedrone and methylone) in two consecutive years (2010 and 2011) at an annual music festival.Design and MethodsDaily composite wastewater samples, representative of the festival, were collected from the on-site wastewater treatment plant and analysed for drug metabolites. Data over 2 years were compared using Wilcoxon matched-pair test. Data from 2010 festival were compared with data collected at the same time from a nearby urban community using equivalent methods.ResultsConventional illicit drugs were detected in all samples whereas emerging illicit psychostimulants were found only on specific days. The estimated per capita consumption of MDMA, cocaine and cannabis was similar between the two festival years. Statistically significant (P