Assessing recurrence of depression using a zero-inflated negative binomial model: A secondary analysis of lifelog data
Assessing recurrence of depression using a zero-inflated negative binomial model: A secondary analysis of lifelog data
复制标题
DOI：
10.1016/j.psychres.2021.113919
复制
发表时间：
2021-04-14
影响因子：
11.3
通讯作者：
Furukawa, Toshi A.
中科院分区：
文献类型：
--
作者：
Kumagai, Narimasa;Tajika, Aran;Furukawa, Toshi A.
在研究抑郁症复发时，研究人员应该注意医生的评估与患者的感知相对应的情况。然而，当医生怀疑复发而不是患者（假阴性零）时，他们还应该关注复发的潜在迹象。由于假阴性会延迟诊断和治疗，我们的目的是调查“无所事事”作为一个预测因素，影响没有复发的警报信号，并估计抑郁症复发的计数。使用智能手机应用程序和可穿戴设备收集了89名缓解抑郁症患者一年多的生活日志数据。复发性抑郁症的定义采用日本版的Kessler心理困扰量表和患者健康问卷-9评分。对人群平均参数的估计表明，每天无所事事的时间增加了两到四周后复发抑郁症的机会。每天暴露在紫外线下会降低抑郁症复发率。虽然长时间的睡眠是2 ~ 4周后抑郁症复发为零的决定因素，但每天无所事事的时间可以否定它。因此，每天无所事事的时间可以减少抑郁症复发的过度分散，我们可以通过考虑无所事事的变化来准确地测量复发性抑郁症。
When studying recurrence of depression, researchers should pay attention to cases where physicians' assessment corresponds to the patients' perception. However, they should also focus on potential signs of recurrence when the recurrence is suspected by the physicians but not the patients (false-negative zeros). Because false negatives can delay diagnosis and treatment, we aimed to investigate "sitting idly" as a predictor influencing no alert sign of recurrence and estimated the counts of recurrence of depression. A smartphone application and a wearable device were used to collect lifelog data from 89 remitted depressive patients over one year. Recurrent depression was defined using the Japanese version of the Kessler Psychological Distress Scale and Patient Health Questionnaire-9 scores. Estimates of the population-averaged parameters indicated that daily hours of sitting idly increased the chances of recurrent depression occurring two to four weeks later. Exposure to daily ultraviolet light reduced depression relapse. Although long sleep was a determinant of zero outcome of the recurrence of depression after two to four weeks, daily hours of sitting idly can negate it. Thus, daily hours of sitting idly could reduce overdispersion of the recurrence of depression, and we could measure recurrent depression accurately by considering changes in sitting idly.