Multi-optical signal channel gold nanoclusters and their application in heavy metal ions sensing arrays
Multi-optical signal channel gold nanoclusters and their application in heavy metal ions sensing arrays
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DOI：
10.1039/d0tc05160h
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发表时间：
2021-03
影响因子：
6.4
通讯作者：
Yunyun Gui;Yiheng Wang;Chiyang He;Z. Tan;Lingfeng Gao;Wei Li;Huiting Bi
中科院分区：
文献类型：
--
作者：
Yunyun Gui;Yiheng Wang;Chiyang He;Z. Tan;Lingfeng Gao;Wei Li;Huiting Bi
为了提高阵列传感系统的性能，设计了一种新的一锅法制备多光信号通道金纳米团簇（MS-AuNCs），包括化学发光（CL）和荧光（FL）。并从MS-AuNCs的CL和FL光谱中提取多个参数，实现了传感阵列对重金属离子鉴别的优异性能。在该合成策略中，11-巯基十四酸（MUA）作为封盖剂首先形成Au(I) -硫醇配合物。然后引入鲁米诺作为还原剂还原Au(I) -硫醇配合物，并作为化学发光试剂形成MS-AuNCs。与以往制备发光功能化纳米粒子的方法相比，该方法可一步获得具有多个光信号通道的功能化纳米粒子，且方法简单。所得的MS-AuNCs在与二氧化氢反应时表现出优异的CL性能。MS-AuNCs荧光发射光谱的峰位不随激发波长的增加而移位。MS-AuNCs亮橙色的荧光很强，足以用肉眼看到。基于从MS-AuNCs的CL和FL光谱中提取的5个参数，开发了一种用于识别重金属离子的传感阵列。该传感策略可以区分不同浓度的七种重金属离子，包括Al3+、Co2+、Cr3+、Cu2+、Hg2+、Pb2+和Zn2+。此外，本研究还首次获得了新型的多光信号通道金纳米团簇，在生物检测和生物成像等领域有更广阔的应用前景。
To improve the performance of an array-based sensing system, a novel one-pot method was designed to prepare multi-optical signal channel gold nanoclusters (MS-AuNCs), including chemiluminescence (CL) and fluorescence (FL). And multi parameters were extracted from the CL and FL spectra of MS-AuNCs to realize the excellent performance of sensing arrays for heavy metal ion differentiation. In this synthetic strategy, 11-mercaptoundecanoic acid (MUA) was used as the capping agent to form Au(I)–thiol complexes first. Then luminol was introduced as a reductant to reduce the Au(I)–thiol complexes and as a chemiluminescent reagent to form MS-AuNCs. Compared with previous methods for preparing luminescent functionalized nanoparticles, the proposed method could obtain functionalized nanoparticles with multi-optical signal channels in one step and is much simple. The obtained MS-AuNCs exhibited excellent CL performance when reacting with hydrogen dioxide. The peak position of the MS-AuNCs FL emission spectra does not shift as increasing excitation wavelengths. The bright orange FL of MS-AuNCs was strong enough to be seen with naked eye. Based on five parameters extracted from the CL and FL spectra of MS-AuNCs, one sensing array was developed for distinguishing heavy metal ions. The sensing strategy could differentiate seven heavy metal ions with different concentrations, including Al3+, Co2+, Cr3+, Cu2+, Hg2+, Pb2+ and Zn2+. Moreover, novel multi-optical signal channel gold nanoclusters were obtained for the first time in this work, which may find more promising applications in fields such as bioassays and bioimaging.