Prognostic utility of microvolt T-wave alternans in risk stratification of patients with ischemic cardiomyopathy
Prognostic utility of microvolt T-wave alternans in risk stratification of patients with ischemic cardiomyopathy
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DOI：
10.1016/j.jacc.2005.11.079
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发表时间：
2006-05-02
影响因子：
24
通讯作者：
Chan, PS
中科院分区：
文献类型：
--
作者：
Chow, T;Kereiakes, DJ;Chan, PS
本研究的目的是评估微伏T波电交替（MTWA）是否是缺血性心肌病患者死亡率的独立预测因子。背景微伏T波电交替已被提出作为一种有效的工具，用于识别缺血性心肌病高危患者，这些患者可能受益于植入式心律转复除颤器（ICD）治疗。然而，早期的研究在控制MTWA阴性和非阴性（阳性和不确定）患者之间基线差异的能力方面受到限制。
OBJECTIVES The purpose of this study was to assess if microvolt T-wave alternans (MTWA) is an independent predictor of mortality in patients with ischemic cardiomyopathy.BACKGROUND Microvolt T-wave alternans has been proposed as an effective tool for identifying high-risk patients with ischemic cardiomyopathy who are likely to benefit from implantable cardioverter-defibrillator (ICD) therapy. However, earlier studies have been limited in their ability to control for baseline differences between MTWA-negative and -non-negative (positive and indeterminate) patients.METHODS We enrolled 768 consecutive patients with ischemic cardiomyopathy (left ventricular ejection fraction