Life-course socio-economic disadvantage and late-life cognitive functioning in Taiwan: results from a national cohort study
Life-course socio-economic disadvantage and late-life cognitive functioning in Taiwan: results from a national cohort study
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DOI：
10.1093/inthealth/ihu046
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发表时间：
2014-12-01
影响因子：
2.5
通讯作者：
Fuh, Jong-Ling
中科院分区：
文献类型：
--
作者：
Chiao, Chi;Botticello, Amanda;Fuh, Jong-Ling
背景：晚年认知功能的下降在社会经济地位（SES）群体之间差异很大，但这些影响是否与儿童和成人社会经济地位有关，与在个体生命过程中积累的社会经济地位影响有关，我们知之甚少。方法：本研究以台湾2944名老年人为研究对象，历时18年，评估社会经济劣势对老年人晚年认知功能的影响。认知功能评估使用简短的便携式心理状态问卷量表。在童年和成年期间累积的终生社会经济劣势包括父亲的教育和职业以及参与者的教育和职业。结果：使用多种混合效应模型的多变量分析表明，童年SES的影响在很大程度上可以用成年SES来解释，成年后不利的SES进一步加剧了晚年认知功能的下降(β = -0.02; p
Background: Declines in late-life cognitive functioning differ greatly between socio-economic status (SES) groups, but little is known about whether these effects are related to child and adult SES versus SES effects that accumulate over the individual's life course.Methods: An 18-year longitudinal national sample of older adults from Taiwan (n=2944) was used to estimate the effect of socio-economic disadvantage over the individual's life course on cognitive functioning during late life. Cognitive functioning was assessed using the brief Short Portable Mental Status Questionnaire scale. Life-course socio-economic disadvantage, as accrued during childhood and adulthood, included measures of paternal education and occupation and participant's education and occupation.Results: Multivariate analyses using various mixed-effects models showed that the effects of childhood SES could be largely explained by adult SES and that disadvantageous SES in adulthood further exacerbated declines in late-life cognitive functioning (beta= -0.02; p