New onset or exacerbation of psoriatic skin lesions in patients with definite rheumatoid arthritis receiving tumour necrosis factor α antagonists
New onset or exacerbation of psoriatic skin lesions in patients with definite rheumatoid arthritis receiving tumour necrosis factor α antagonists
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DOI：
10.1136/ard.2005.037424
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发表时间：
2006-03-01
影响因子：
27.4
通讯作者：
Burmester, GR
中科院分区：
文献类型：
--
作者：
Kary, S;Worm, M;Burmester, GR
背景资料：肿瘤坏死因子α（TNF α）的阻断在风湿性疾病中非常有效，特别是在类风湿性关节炎（RA）、强直性脊柱炎和银屑病关节炎中。此外，TNF α拮抗剂也已被证明可以显着减少银屑病皮肤lesions.Case reports：一系列的9例RA患者谁是治疗与不同类型的TNF α拮抗剂和谁意外地开发一个新的发病或加重银屑病皮肤病变的报告。
Background: Blockage of tumour necrosis factor alpha (TNF alpha) is highly effective in rheumatic diseases, especially in rheumatoid arthritis (RA), ankylosing spondylitis, and psoriatic arthritis. Furthermore, TNF alpha antagonists have also been shown to significantly reduce psoriatic skin lesions.Case reports: A series of nine patients with RA who were treated with different types of TNF alpha antagonists and who unexpectedly developed either a new onset or an exacerbation of psoriatic skin lesions are reported.