The polymorphic prelude to Bateson-Dobzhansky-Muller incompatibilities
The polymorphic prelude to Bateson-Dobzhansky-Muller incompatibilities
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DOI：
10.1016/j.tree.2011.11.004
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发表时间：
2012-04-01
影响因子：
16.8
通讯作者：
Cutter, Asher D.
中科院分区：
文献类型：
--
作者：
Cutter, Asher D.
物种形成研究在很大程度上假设生殖隔离的遗传原因是固定的、不同的等位基因的作用，这些等位基因相互作用导致杂交后代的遗传问题：贝特森-多布赞斯基-穆勒不相容性。然而，许多最近的研究表明，大量的遗传多态性物种内的杂种不亲和性，在这里被称为可变生殖隔离（VRI）。在这篇评论中，我概述了这种普遍现象的原因和重要性。我还确定了新的挑战，量化的相对贡献，生殖隔离的固定等位基因与多态性的，这些贡献的变化过程中的物种形成。明确整合VRI到物种形成理论将有助于量化遗传漂变和选择在物种形成中的相对作用，但这种合成需要大量的新的理论和实证研究的贡献。
Speciation research has largely assumed that the genetic causes of reproductive isolation are the work of fixed, divergent alleles that interact to cause genetic problems in hybrids: Bateson-Dobzhansky-Muller incompatibilities. However, many recent studies demonstrate substantial heritable polymorphism within species for hybrid incompatibility, herein called variable reproductive isolation (VRI). In this review, I outline the causes and importance of this general phenomenon. I also identify the new challenges of quantifying the relative contributions to reproductive isolation of fixed alleles versus polymorphism's, and the change in these contributions over the course of speciation. Explicit integration of VRI into speciation theory will help to quantify the relative roles of genetic drift and selection in speciation, but this synthesis requires substantial new contributions from both theory and empirical studies.