Innovating Chinese Herbal Medicine: From Traditional Health Practice to Scientific Drug Discovery.
Innovating Chinese Herbal Medicine: From Traditional Health Practice to Scientific Drug Discovery.
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DOI：
10.3389/fphar.2017.00381
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发表时间：
2017
影响因子：
5.6
通讯作者：
Pei J
中科院分区：
文献类型：
--
作者：
Gu S;Pei J
作为当代主要的替代医学之一，中医药在中国社会的影响持续不断，并开始引起西医界的学术关注。本文旨在从叙事和科学两个角度考察中医的精华分支--中草药。中医是一种源于中国哲学和宗教的传统养生方法，秉持整体论和身体平衡的信念。随着正统医学和科学在过去几个世纪的发展，中医药学也抓住机会，从传统的健康实践转变为科学的药物发现，这一著名的草药衍生药物的故事就是例证。然而，受其文化和创立原则的阻碍，中医药学面临着科学惯例提出的研究范式的问题。为了解决这些问题，我们讨论了中医学与科学关系的两个基本问题，并在此基础上坚持了科学研究中的方法论还原范式。最后，讨论了21世纪中医药学的当代叙事，以期在科学研究的同时保存这一医学传统。
As one of the major contemporary alternative medicines, traditional Chinese medicine (TCM) continues its influence in Chinese communities and has begun to attract the academic attention in the world of western medicine. This paper aims to examine Chinese herbal medicine (CHM), the essential branch of TCM, from both narrative and scientific perspectives. CHM is a traditional health practice originated from Chinese philosophy and religion, holding the belief of holism and balance in the body. With the development of orthodox medicine and science during the last centuries, CHM also seized the opportunity to change from traditional health practice to scientific drug discovery illustrated in the famous story of the herb-derived drug artemisinin. However, hindered by its culture and founding principles, CHM faces the questions of the research paradigm posed by the convention of science. To address these questions, we discussed two essential questions concerning the relationship of CHM and science, and then upheld the paradigm of methodological reductionism in scientific research. Finally, the contemporary narrative of CHM in the 21st century was discussed in the hope to preserve this medical tradition in tandem with scientific research.