Henry Kempe and the birth of vaccinia immune globulin.
Henry Kempe and the birth of vaccinia immune globulin.
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亨利·肯佩和牛痘免疫球蛋白的诞生。
DOI：
10.1086/423005
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发表时间：
2004
期刊：
影响因子：
--
通讯作者：
Bray,Mike
中科院分区：
文献类型：
--
作者：
Bray,Mike
生物恐怖分子重新引入天花的威胁迫使公共卫生当局重新审视长期以来被认为已被永远搁置的程序。目前使用的天花疫苗与1972年美国结束普遍接种之前使用的疫苗相同，其接种方法与1796年爱德华詹纳的程序几乎没有区别。准备应对疫苗接种的并发症意味着恢复20世纪50年代初开发的一种疗法，该疗法采用牛痘免疫球蛋白（VIG），这是一种从接种疫苗的个体的混合血浆中提取的产品。
The threat of a bioterrorist reintroduction of smallpox has forced public health authorities to dust off procedures long thought to have been put away forever. The current smallpox vaccine is the same as that used before universal vaccination ended in the United States in 1972, and its method of administration differs little from Edward Jenner’s procedure of 1796. Preparing to deal with the complications of vaccination has meant reviving a therapy developed in the early 1950s that employs vaccinia immune globulin (VIG), a product derived from the pooled plasma of vaccinated individuals.