Regional cerebral blood flow changes in human brain related to ipsilateral and contralateral complex hand movements - a PET-study
Regional cerebral blood flow changes in human brain related to ipsilateral and contralateral complex hand movements - a PET-study
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DOI：
10.1046/j.1460-9568.1998.00237.x
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发表时间：
1998-07-01
影响因子：
3.4
通讯作者：
Yonekura, Y
中科院分区：
文献类型：
--
作者：
Kawashima, R;Matsumura, M;Yonekura, Y
本研究的目的是探讨单侧复杂手部动作时大脑皮层运动区的激活，以及与运动技能学习相关的运动区。用正电子发射断层扫描技术测量8名右利手健康男性志愿者在两个球旋转任务中使用右手、使用左手的相同任务和两个控制任务期间的局部脑血流量（rCBF）。在两球旋转任务中，受试者用右手或左手旋转两个相同的铁球。required.io在控制任务中，他们被要求每只手拿着两个球，不能移动。每一个单侧手部运动都会激活双侧的初级运动区、运动前区和小脑。与此相反，辅助运动区适当的激活，只有对侧的手运动。此外，我们发现运动前区的rCBF与运动任务训练中技能的提高程度呈正相关。结果表明，复杂的手部动作是由双侧的初级运动区、运动前区和小脑组织的，在复杂的手指动作过程中，运动皮层的功能不对称性并不明显，运动前区可能在运动技能学习中发挥重要作用。
The purpose of this study was to investigate the cortical motor areas activated in relation to unilateral complex hand movements of either hand, and the motor area related to motor skill learning. Regional cerebral blood flow (rCBF) was measured in eight right-handed healthy male volunteers using positron emission tomography during a two-ball-rotation task using the right hand, the same task using the left hand and two control tasks. In the two-ball-rotation tasks, subjects were required.io rotate the same two iron balls either with the right or left hand. In the control task, they were required to hold two balls in each hand without movement. The primary motor area, premotor area and cerebellum were activated bilaterally with each unilateral hand movement. In contrast, the supplementary motor area proper was activated only by contralateral hand movements. In addition, we found a positive correlation between the rCBF to the premotor area and the degree of improvement in skill during motor task training. The results indicate that complex hand movements are organized bilaterally in the primary motor areas, premotor areas and cerebellum, that functional asymmetry in the motor cortices is not evident during complex finger movements, and that the premotor area may play an important role in motor skill learning.