Computational fluid dynamics with stents: quantitative comparison with particle image velocimetry for three commercial off the shelf intracranial stents
Computational fluid dynamics with stents: quantitative comparison with particle image velocimetry for three commercial off the shelf intracranial stents
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DOI：
10.1136/neurintsurg-2014-011468
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发表时间：
2016-03-01
影响因子：
4.8
通讯作者：
Pereira, Vitor Mendes
中科院分区：
文献类型：
--
作者：
Bouillot, Pierre;Brina, Olivier;Pereira, Vitor Mendes
背景和目的颅内动脉瘤（IA）支架置入术中的计算流体动力学（CFD）验证仍然缺乏，无法可靠地预测易发生闭塞的血流动力学、探测（特别是速度降低）和流型变化。本研究比较CFD结果与粒子成像测速（PIV）为三个商业现成的（COTS）stentsofdifferent material density.Material和methods最近开发的均匀和高精度的多时间滞后PIV方法应用于侧壁动脉瘤植入前和植入后的三个COTS支架高，中，低材料密度。测得的激光片流的模式和速度降低与CFD结果进行了比较，并与支架材料density.Results速度降低无支架的高和低孔隙率支架IA是在良好的协议，而流动模式的变化是完全匹配的无支架和高孔隙率支架IA。差的CFD-PIV匹配在IA中发现中等孔隙率stents.Conclusions CFD再现完全PIV测量在无支架和高孔隙率stented IA。对于低孔隙率支架，CFD再现了颈部附近的流速降低和高流速，而在圆顶处发现了缓慢流动的显著不匹配。CFD无法将PIV与发生血流动力学转变的中等孔隙率支架匹配。
Background and purpose Validation of computational fluid dynamics (CFD) in stented intracranial aneurysms (IAs) is still lacking, to reliably predict prone to occlusion hemodynamics, probing, in particular, velocity reduction, and flow pattern changes. This study compares CFD outcome with particle imaging velocimetry (PIV) for three commercial off the shelf (COTS) stents of different material densities.Material and methods The recently developed uniform and high precision multi-time lag PIV method was applied to a sidewall aneurysm before and after implantation of three COTS stents with high, intermediate, and low material densities. The measured laser sheet flow patterns and velocity reductions were compared with CFD results and correlated with stent material density.Results Velocity reduction was in good agreement for unstented high and low porosity stented IA, while flow pattern change was fully matched for unstented and high porosity stented IA. Poor CFD-PIV matching in IA was found for intermediate porosity stents.Conclusions CFD reproduced fully PIV measurements in unstented and high porosity stented IAs. With low porosity stents, CFD reproduced velocity reduction and high velocities close to the neck, while a marked mismatch on sluggish flow was found at the dome. CFD was unable to match PIV with intermediate porosity stents for which hemodynamic transition occurred.