Dynamic changes of views on the brain changes of Cushing's syndrome using different computer-assisted tool
Dynamic changes of views on the brain changes of Cushing's syndrome using different computer-assisted tool
复制标题
DOI：
10.1007/s11154-020-09540-1
复制
发表时间：
2020-03-01
影响因子：
8.2
通讯作者：
Xing, Bing
中科院分区：
文献类型：
--
作者：
Gao, Lu;Liu, Lu;Xing, Bing
库欣综合征（CS）为评估慢性皮质醇增多症对人脑的神经毒性作用提供了一个独特的模型。随着不同计算机辅助工具的不断发展，出现了四个研究阶段，每个阶段都有自己的珍珠和陷阱。本文综述了当前认知的发展，并描述了在当前人工智能和大数据飞速发展的时代，对CS脑变化的看法的动态变化。GC对脑的不良影响同时表现在结构、功能和细胞水平上。
Cushing's syndrome (CS) provides a unique model for assessing the neurotoxic effect of chronic hypercortisolism on human brains. With the ongoing development of different computer-assisted tools, four research stages emerged, each with its own pearls and pitfalls. This review summarizes current knowledge and describes the dynamic changes of views on the brain changes of CS, especially in the current era of the rapid development of artificial intelligence and big data. The adverse effects of GC on brain are proven to be on structural, functional and cellular levels at the same time.