Muscarinic M2 antagonists: anthranilamide derivatives with exceptional selectivity and in vivo activity

Muscarinic M2 antagonists: anthranilamide derivatives with exceptional selectivity and in vivo activity
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DOI:
10.1016/j.bmc.2003.11.005
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发表时间:
2004-01-15
影响因子:
3.5
通讯作者:
Greenlee, WJ
Greenlee, WJ
中科院分区:
医学3区
文献类型:
--
作者:
Clader, JW;Billard, W;Greenlee, WJ

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邻氨基苯甲酰胺类似物,如23是有效的和高选择性的毒蕈碱M2拮抗剂,也显示出良好的口服生物利用度和体内活性。(C)2003爱思唯尔有限公司。保留所有权利。
Anthranilamide analogues such as 23 are potent and highly selective muscarinic M2 antagonists that also show good oral bioavailability and in vivo activity. (C) 2003 Elsevier Ltd. All rights reserved.