Low birthweight in New York city and upstate New York following the events of September 11th
Low birthweight in New York city and upstate New York following the events of September 11th
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DOI：
10.1093/humrep/dem301
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发表时间：
2007-11-01
影响因子：
6.1
通讯作者：
Toniolo, Paolo G.
中科院分区：
文献类型：
--
作者：
Eskenazi, Brenda;Marks, Amy R.;Toniolo, Paolo G.
背景：我们研究了2001年9月11日世界贸易中心灾难后纽约市（NYC）和纽约北部的妊娠结局。方法：采用正交试验设计使用纽约居民的出生证明数据（n = 1660，401例出生），我们估计了9月11日之后一周与三周前的低出生体重（LBW：< 2500 g）和早产（< 37周）的风险，以及灾难后10个四周的间隔与前两年的这些间隔。为了证实回归结果，我们使用了时间序列分析。研究结果：在纽约市9月11日之后的一周，我们观察到出生体重< 1500 g的调整后比值为1.44（P = 0.07），出生体重1500-1999 g的调整后比值为1.67（P = 0.01），但2000-2499 g的比值降低。我们没有发现任何地方的LBW或早产的立即变化。在扩展分析中，我们发现，在这两个地区，新年前后和灾后33-36周出生< 1500 g的几率增加，灾后几周中度早产的几率降低。时间序列分析得出了类似的结果。结论：2001年9月11日在纽约市发生的事件与出生体重< 2000 g的婴儿的立即增加、早产的轻微延迟减少以及接触围产期或前两个孕期的婴儿的LBW延迟增加有关。压力可能有助于观察到的关联。
BACKGROUND: We examined pregnancy outcomes in New York City (NYC) and upstate New York after the September 11, 2001 World Trade Center disaster. METHODS: Using birth certificate data for NY residents (n = 1660,401 births), we estimated risk of low birthweight (LBW: < 2500 g) and preterm birth (< 37 weeks) one week after September 11th versus three weeks before, and for 10 four-week intervals post-disaster versus these intervals in the two previous years. To corroborate regression results, we used time-series analysis. RESULTS: One week after September 11th in NYC, we observed an adjusted odds of 1.44 for births < 1500 g (P = 0.07) and 1.67 for births 1500-1999 g (P = 0.01), but a decreased odds of 2000-2499 g. We found no immediate change in LBW upstate or preterm in either location. In extended analyses, we found, in both locations, increased odds of < 1500-g births around New Year and 33-36 weeks post-disaster and decreased odds of moderate preterm for several weeks post-disaster. Time-series analyses yielded similar findings. CONCLUSIONS: The events of September 11, 2001 in NYC were associated with immediate increases in births < 2000 g, slightly delayed decreased preterm delivery, and delayed increases in LBW among infants exposed periconception or in the first two trimesters. Stress may contribute to observed associations.