CHANGES IN TESTICULAR CANCER IN SCOTLAND
CHANGES IN TESTICULAR CANCER IN SCOTLAND
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DOI：
10.1016/0277-5379(87)90286-0
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发表时间：
1987-06-01
期刊：
影响因子：
--
通讯作者：
ROBERTSON, AG
中科院分区：
文献类型：
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作者：
BOYLE, P;KAYE, SB;ROBERTSON, AG
本文有两个目的。首先描述苏格兰生殖细胞睾丸癌的时间模式，既作为单一实体又作为组织学亚型（纯）精原细胞瘤和畸胎瘤。 1959 年至 1984 年间，发病率上升了 50% 以上，其中精原细胞瘤的发病率仅略有上升，总体上升的大部分是由于亚型畸胎瘤的大幅上升所致。其次，根据过去 25 年临床试验和临床系列报道的生存率改善情况，调查新疗法对苏格兰生殖细胞睾丸癌死亡率的影响。死亡率的时间模式发生了显着的变化，但不能用发病率的变化来解释。发病率上升与死亡率下降之间的差距不断扩大，在 15-44 岁高危年龄组中尤为明显，这表明苏格兰这种恶性肿瘤患者的预后正在改善。
There are two purposes to this paper. Firstly to describe the temporal pattern of germ-cell testicular cancers in Scotland, both as a single entity and as the histological sub-types (pure) seminoma and teratoma. Incidence rates rose by over 50% between 1959 and 1984, with the rates of seminoma increasing only marginally and the majority of the overall increase accounted for by the substantial increase observed among the sub-type teratoma. Secondly, to investigate the impact of new therapies on the mortality rate from germ-cell testicular cancer in Scotland in the light of improvement in survival rate reported during the last 25 years from clinical trials and clinical series. Noticeable changes have occurred in the temporal pattern of mortality which cannot be explained by changes in incidence. The ever-widening gap between the increasing incidence rate and the declining mortality rate, particularly apparent in the high-risk age group 15-44, indicates an improving prognosis for patients with this malignancy in Scotland.