The estimation of cardiac function from the rotary blood pump.
The estimation of cardiac function from the rotary blood pump.
复制标题
通过旋转血泵评估心脏功能。
DOI：
10.1046/j.1525-1594.2001.06861.x
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发表时间：
2001
影响因子：
2.4
通讯作者：
Y. Sankai
中科院分区：
文献类型：
--
作者：
K. Nakata;M. Shiono;K. Akiyama;Y. Orime;A. Saito;H. Tutomu;N. Negishi;Y. Sezai;Y. Sankai
旋转血泵是心脏移植的桥梁。已描述了植入左心室辅助装置（LVAD）后患者的机械、组织学和生化改善。因此，旋转血泵可作为心肌功能恢复的桥梁。然而，与搏动泵不同，旋转血泵不能停止以估计心脏功能：如果旋转血泵停止，将发生回流。在这项研究中，一种新的方法，可以估计心脏功能没有泵停止进行了审查。本急性研究的受试者为6只猪。泵作为LVAD植入：入口套管插入左心室，出口套管插入升主动脉。在舒张期以0 L/min的泵流速调节电机速度。然后，左心室压力的dp/dt和驱动器的外部冲程功之间的关系进行了检查。该方法在正常、高动力和心力衰竭条件下进行了研究。左室压力的dp/dt与作动器的外行程功呈高度正相关。该方法简便、实用，可用于无停泵状态下的心功能评估。
The rotary blood pump is implanted as a bridge to cardiac transplantation. Mechanical, histological, and biochemical improvements have been described in patients after implantation of left ventricular assist devices (LVADs). Thus, the rotary blood pump might be used as a bridge to recovery of myocardial function. However, unlike a pulsatile pump, the rotary blood pump cannot be stopped to estimate cardiac function: if the rotary blood pump stops, backflow will occur. In this study, a new method that can estimate cardiac function without pump stop was examined. Six pigs were the subjects of this acute study. The pump was implanted as an LVAD: the inlet cannula was inserted into the left ventricle, and the outlet cannula was inserted into the ascending aorta. The motor speed was regulated at a pump flow rate of 0 L/min at diastolic phase. Then, the relationship between the dp/dt of left ventricular pressure and external stroke work of actuator was examined. This method was studied at normal, hyperdynamic, and heart-failure conditions. There was a high positive correlation between the dp/dt of left ventricular pressure and external stroke work of actuator. This method is useful and simple to estimate cardiac function without pump stop.