Docetaxel/Cyclophosphamide-Induced Phototherapy Recall
Docetaxel/Cyclophosphamide-Induced Phototherapy Recall
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多西紫杉醇/环磷酰胺引起的光疗召回
DOI：
10.1177/0897190015627531
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发表时间：
2016
期刊：
影响因子：
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通讯作者：
S. Chehab
中科院分区：
文献类型：
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作者：
Steven P. Ludlow;S. Chehab
光疗回忆可能会意外地发生，作为常用药物和化疗治疗的结果。这些反应是罕见的。回忆反应是一种炎症反应，由许多药物引发。环磷酰胺和多西他赛是广泛使用的化疗药物，可用于治疗许多不同的恶性肿瘤。光疗回忆的病理生理学还不清楚。这种情况强调了从业人员需要意识到这种潜在的反应，即使紫外线暴露可能发生在遥远的过去。据我们所知，我们提出了第一个光疗回忆皮炎，发生在环磷酰胺和多西他赛诱导的紫外线暴露后数年。这种药物的给药频率和这种不良反应的深刻影响使该病例对医学文献做出了重要贡献。
Phototherapy recall can occur unexpectedly as a result of treatment with commonly used medications and chemotherapy. These reactions are rare. The recall reaction is an inflammatory response that is triggered by many medications. Cyclophosphamide and docetaxel are widely used chemotherapeutic agents that are useful in the management of many different malignancies. The pathophysiology of phototherapy recall is not clearly understood. This case highlights the need for practitioners to be aware of this potential reaction, even though UV exposure may have occurred in the distant past. We present, to the best of our knowledge, the first phototherapy recall dermatitis that occurred years after UV exposure induced by cyclophosphamide and docetaxel. The frequency of administration of this drug and the profound implications of this adverse effect make this case an important contribution to the medical literature.