From "A family of NICU graduates" to "A family of four".
From "A family of NICU graduates" to "A family of four".
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DOI：
10.1038/s41390-022-02234-1
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发表时间：
2022-09
影响因子：
3.6
通讯作者：
Chandrasekharan, Praveen
中科院分区：
文献类型：
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作者：
Chandrasekharan, Praveen
感谢儿科研究再次强调我们的工作。从上一个亮点开始，我们已经走过了很长的路，无论是个人还是专业。我们确实从“一个NICU毕业生家庭”（我们的长子早产，住在新生儿重症监护室（NICU））到“一个四口之家”（第二个儿子按时出生）。我们的个人经验将给所有早产儿的父母带来一线希望，有时统计数据（第一次自然分娩后第二次早产的可能性估计为30-40%）并不总是对我们不利（图1）。[1]从我的研究员生涯开始，我就对转化和临床研究感兴趣，评估出生时胎儿过渡期心肺神经方面的适应性（图2）。我目前发表的研究，“窒息早产儿模型中新生儿复苏期间的胎盘输血”，有助于理解新生儿复苏期间不需要胸外按压的抑郁早产儿模型中延迟脐带夹紧和脐带挤奶的作用。2我们还研究了在该模型中氧暴露和延迟脊髓夹闭的相互作用。3.下一步，我们打算了解完整脐带复苏在抑郁性早产模型中的作用，沿着氧暴露和氧化损伤的相互作用。
Thanks to Pediatric Research for highlighting our work again. We have come a long way from the last highlight, both personally and professionally. We did go from “A family of NICU graduates”(neonatologist parents with our firstborn being premature with a neonatal intensive care unit (NICU) stay) to “A family of four”(the second son came on time). Our personal experience will give a ray of hope to all parents of premature babies that sometimes statistics (the chances of having a second preterm birth after the first spontaneous one is estimated to be 30–40%) are not always against us (Fig. 1). 1Since my fellowship days, I have been interested in translational and clinical research, evaluating the adaptation of cardiopulmonary-neural aspects during the fetal transition at birth (Fig. 2). My current published research,“Placental transfusion during neonatal resuscitation in an asphyxiated preterm model,” helps understand the role of delayed cord clamping and cord milking in a depressed preterm model during neonatal resuscitation without requiring chest compressions. 2 We have also studied the interaction of oxygen exposure and delayed cord clamping in this model. 3 Moving forward, we intend to understand the role of the intact umbilical cord resuscitation in a depressed preterm model, along with the interaction of oxygen exposure and oxidative injury.
DOI：
10.3390/children8040307
发表时间：
2021-04-17
期刊：
Children (Basel, Switzerland)
影响因子：
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作者：
Chandrasekharan P;Gugino S;Helman J;Koenigsknecht C;Nielsen L;Bradley N;Nair J;Agrawal V;Bawa M;Mari A;Rawat M;Lakshminrusimha S
通讯作者：
Lakshminrusimha S