Preparation of Functionalized 2,7-Naphthyridines by Directed Lithiation with (2,2,6,6-Tetramethylpiperidyl)lithium and Their Regioselective Iron-Catalyzed Cross Couplings
Preparation of Functionalized 2,7-Naphthyridines by Directed Lithiation with (2,2,6,6-Tetramethylpiperidyl)lithium and Their Regioselective Iron-Catalyzed Cross Couplings
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DOI：
10.1055/s-0035-1560703
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发表时间：
2016-01-01
期刊：
影响因子：
2
通讯作者：
Knochel, Paul
中科院分区：
文献类型：
--
作者：
Greiner, Robert;Blanc, Romain;Knochel, Paul
本文报道了以2，2，6，6-四甲基哌啶基锂为碱对2，7-萘啶进行区域选择性官能化反应，并通过区域选择性铁催化的交叉偶联反应，选择性地得到四烷基化的2，7-萘啶。
We report the regioselective functionalization of 2,7-naphthyridines by using (2,2,6,6-tetramethylpiperidyl)lithium as a base, together with the regioselective iron-catalyzed cross-coupling reactions of the products to give tetraalkylated 2,7-naphthyridines selectively.