ELEMENTARY PROPERTIES OF CARDIAC CALCIUM CHANNELS - A BRIEF REVIEW

ELEMENTARY PROPERTIES OF CARDIAC CALCIUM CHANNELS - A BRIEF REVIEW
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DOI:
10.1139/y88-201
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发表时间:
1988-09-01
影响因子:
2.1
通讯作者:
HESS, P
HESS, P
中科院分区:
医学4区
文献类型:
--
作者:
HESS, P

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本文综述了通过单细胞和单通道的电生理记录对心脏钙通道功能的新认识。两种不同类型的心脏钙通道的统一属性进行了讨论和对比,并特别强调了通道渗透,门控,外源性和内源性配体的调制机制。
This article reviews the new insight into the function of cardiac calcium channels made possible by electrophysiological recordings from single cells and single channels. The unitary properties of the two different types of cardiac calcium channels are discussed and contrasted, and special emphasis is given to the mechanisms of channel permeation, gating, and modulation by exogenous and endogenous ligands.