Is Autophagy Dysfunction a Key to Exfoliation Glaucoma?
Is Autophagy Dysfunction a Key to Exfoliation Glaucoma?
复制标题
DOI：
10.1097/ijg.0000000000000606
复制
发表时间：
2018-03
影响因子：
2
通讯作者：
Bernstein AM
中科院分区：
文献类型：
--
作者：
Wolosin JM;Ritch R;Bernstein AM
在这篇简短的报告中，我们回顾了以前的工作，对剥脱性青光眼的蛋白质和细胞来源的鉴定，并描述了我们最近发现的Tenon囊成纤维细胞自噬功能障碍，从剥脱综合征青光眼患者手术时，并讨论了这些发现的潜在影响，了解疾病的细胞来源。
In this short report we review previous work toward the identification of the protein and cellular sources of exfoliation glaucoma and described our recent finding on dysfunction of autophagy in Tenon capsule fibroblasts obtained from exfoliation syndrome glaucoma patients at the time of surgery and discuss the potential implications of these findings for understanding the cellular sources of the disease.