Potassium Channels as Targets for Therapeutic Intervention

Potassium Channels as Targets for Therapeutic Intervention
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钾通道作为治疗干预的目标

DOI:
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发表时间:
2005
期刊:
Science's STKE
影响因子:
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通讯作者:
G. Kaczorowski
G. Kaczorowski
中科院分区:
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文献类型:
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作者:
Maria L. Garcia;G. Kaczorowski

文献摘要

被引文献

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The potassium channel superfamily presents a rich source of targets for therapeutic intervention. Indeed, the development of specific potassium channel modulators could lead to the effective treatment of various diseases for which current therapies are clearly suboptimal. Numerous factors play a role in determining whether the successful clinical development of such drugs can ever be achieved. However, the large body of information accumulated over the last few years on the structure and function of potassium channels is expected to drive drug-development efforts in the pharmaceutical industry on these targets, with the ultimate goal of developing therapies that will improve patient quality of life.