Relationship between Vision-Related Quality of Life and Central 10° of the Binocular Integrated Visual Field in Advanced Glaucoma.
Relationship between Vision-Related Quality of Life and Central 10° of the Binocular Integrated Visual Field in Advanced Glaucoma.
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晚期青光眼患者视力相关生活质量与双眼综合视野中心 10° 的关系。
DOI：
10.1038/s41598-019-50677-0
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发表时间：
2019
期刊：
影响因子：
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通讯作者：
Matsumoto S.
中科院分区：
文献类型：
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作者：
Yamazaki Y;Sugisaki K;Araie M;Murata H;Kanamori A;Inoue T;Ishikawa S;Yoshikawa K;Maeda H;Yamada Y;Negi A;Inatani M;Tanihara H;Okinami S;Mizuki K;Mishima K;Uchida K;Matsumoto S.
目的探讨172例晚期青光眼患者双眼综合视野（IVF）中心10°各亚视野的敏感度丧失与视觉相关生活质量（VRQoL）的关系。采用随机森林算法控制IVF各子场之间的相关性，分析了Humphrey Field Analyzer（HFA）10-2程序测量的IVF中8个象限子场的Rasch分析导出的个人能力指数（RADPAI）、年龄、最佳矫正视力（BCVA）、平均总偏差（mTD）之间的关系（10-2 IVF），和用HFA 24-2程序（24-2 IVF）测量的IVF中上/下半野的mTD。对RADPAIs有显著影响的区域为：10-2 IVF的内、外右下象限对用餐和总任务有贡献，10-2 IVF的左下象限对行走、外出和总任务有贡献，24-2 IVF的下半野对行走、外出、用餐、杂项和总任务有贡献; BCVA对字母、句子、穿衣和其他任务的贡献最大。在晚期青光眼患者的日常任务中，不同10-2 IVF子场的损伤影响显著不同。
To investigate the relationships between sensitivity loss in various subfields of the central 10° of the binocular integrated visual field (IVF) and vision-related quality of life (VRQoL) in 172 patients with advanced glaucoma. Using the Random Forest algorithm, which controls for inter-correlations among various subfields of the IVF, we analysed the relationships among the Rasch analysis-derived person ability index (RADPAI), age, best-corrected visual acuity (BCVA), mean total deviations (mTDs) of eight quadrant subfields in the IVF measured with the Humphrey Field Analyzer (HFA) 10-2 program (10-2 IVF), and mTDs of the upper/lower hemifields in the IVF measured with the HFA 24-2 program (24-2 IVF). Significant contributors to RADPAIs were as follows: the inner and outer lower-right quadrants of the 10-2 IVF contributed to the dining and total tasks; the lower-left quadrant of the 10-2 IVF contributed to the walking, going out and total tasks; the lower hemifield of the 24-2 IVF contributed to the walking, going out, dining, miscellaneous and total tasks; and BCVA contributed more to the letter, sentence, dressing and miscellaneous tasks than to others. The impact of damage in different 10-2 IVF subfields differed significantly across daily tasks in patients with advanced glaucoma.