Temporal Properties of Visual Perception on Electrical Stimulation of the Retina
Temporal Properties of Visual Perception on Electrical Stimulation of the Retina
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DOI：
10.1167/iovs.11-9344
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发表时间：
2012-05-01
影响因子：
4.4
通讯作者：
Pelizzone, Marco
中科院分区：
文献类型：
--
作者：
Fornos, Angelica Perez;Sommerhalder, Joerg;Pelizzone, Marco
目的。研究长期植入视网膜前假体的盲人患者电诱发知觉的基本时间特性。方法。九名受试者接受了不同持续时间和脉搏率的孤立刺激。将刺激幅度设置为上舒适水平，并同时激活一组 2 x 2 相邻电极。首先，受试者被要求口头描述他们的视觉感知，特别注意亮度的时间进程。然后，在随后的试验中，他们使用操纵杆描述了亮度时间依赖性，同时提供了操纵杆位置的听觉反馈。 结果。所有受试者在刺激开始时都描述了一种明亮的、定位良好的感知。在整个 10 秒的刺激试验中，只有一名受试者报告了如此明亮、定位良好的视觉感觉。对于其余八个受试者，它或多或少地快速褪色（在四个案例中）
PURPOSE. To investigate the elementary temporal properties of electrically evoked percepts in blind patients chronically implanted with an epiretinal prosthesis.METHODS. Nine subjects were presented with isolated stimuli of variable duration and pulse rate. Stimulation amplitude was set to the upper comfortable level and a group of 2 x 2 adjacent electrodes was simultaneously activated. First, subjects were asked to verbally describe their visual perception paying particular attention to the time-course of brightness. Then, in subsequent trials, they described the brightness time dependence using a joystick while auditory feedback of joystick position was provided.RESULTS. All subjects described a bright, well-localized percept at stimulus onset. Only one subject reported such a bright, well-localized visual sensation during an entire 10-second stimulation trial. For the remaining eight subjects, it faded more or less rapidly (in four cases