RENEWAL OF DIFFUSELY DISTRIBUTED PROTEIN IN OUTER SEGMENTS OF RODS AND CONES
RENEWAL OF DIFFUSELY DISTRIBUTED PROTEIN IN OUTER SEGMENTS OF RODS AND CONES
复制标题
DOI：
10.1016/0042-6989(72)90108-3
复制
发表时间：
1972-01-01
期刊：
影响因子：
1.8
通讯作者：
YOUNG, RW
中科院分区：
文献类型：
--
作者：
BOK, D;YOUNG, RW
视觉细胞外节的蛋白质不断更新。蛋白质在细胞内段合成。在视杆细胞中，而不是在视锥细胞中，整个外节（包括蛋白质）通过不断形成新的盘和平衡地脱落旧盘而更新。在视杆细胞和视锥细胞中，都有一个额外的更新过程，在这个过程中，新的蛋白质扩散分布在旧的椎间盘中。这种扩散性蛋白质更新过程发生的速率在视锥细胞中明显更高。
Proteins in the outer segment of visual cells undergo continual renewal. The protein is synthesized in the cell inner segment. In rods, but not in cones, the entire outer segment (including the protein) is renewed by continual formation of new discs coupled with a balanced shedding of old discs. In both rods and cones, there is an additional renewal process in which new protein becomes diffusely distributed among the old discs. This diffuse protein renewal process takes place at a rate which is significantly higher in cones.