Efficacy of antimicrobial photodynamic therapy in the management of chronic periodontitis: a randomized controlled clinical trial
Efficacy of antimicrobial photodynamic therapy in the management of chronic periodontitis: a randomized controlled clinical trial
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DOI：
10.1111/jcpe.12249
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发表时间：
2014-06-01
影响因子：
6.7
通讯作者：
Subhash, Narayanan
中科院分区：
文献类型：
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作者：
Betsy, Joseph;Prasanth, Chandra S.;Subhash, Narayanan
目的评价抗菌光动力疗法（aPDT）作为刮治和刨根术（SRP）辅助治疗慢性牙周炎的潜力。材料与方法在一项单中心随机对照临床试验中，90例未经治疗的慢性牙周炎患者（女性51例，男性39例）被随机分为SRP联合aPDT治疗组（试验组）和SRP单独治疗组（对照组）。临床参数和口臭记录6个月后治疗由牙周病医生谁是盲目的程序。结果进行组间和组内统计分析。使用非参数秩序方差分析评估两组之间各变量的显著差异。与对照组相比，试验组在3个月和6个月的评估中探测袋深度和临床依恋水平有统计学意义上的显著降低(p
Aim To evaluate the potential of antimicrobial photodynamic therapy (aPDT) as an adjunct to scaling and root planing (SRP) in the treatment of chronic periodontitis. Material and Methods In a single-centred randomized and controlled clinical trial, 90 patients (51 females and 39 males) with untreated chronic periodontitis were randomly assigned to receive SRP with aPDT (test group) or SRP alone (control group). Clinical parameters and halitosis were recorded for 6months after treatment by a periodontist who was blinded to the procedure. Results Inter-group and intra-group statistical analyses were performed. Significant difference between the two groups with respect to each variable was assessed using non-parametric Rank Order ancova. Probing pocket depth and clinical attachment levels showed statistically significant reduction in the test group on evaluation at 3months and 6months as compared to the control group (p