Prefrontal oxygenation correlates to the responses in facial skin blood flows during exposure to pleasantly charged movie.
Prefrontal oxygenation correlates to the responses in facial skin blood flows during exposure to pleasantly charged movie.
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DOI：
10.14814/phy2.13488
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发表时间：
2017-11
影响因子：
2.5
通讯作者：
Ishida T
中科院分区：
文献类型：
--
作者：
Matsukawa K;Endo K;Asahara R;Yoshikawa M;Kusunoki S;Ishida T
我们的实验室报告说，面部皮肤血流量可以作为评估情绪状态的敏感工具。在情绪干预期间，应根据面部皮肤血流量的变化来寻找脑神经相关因素。为了验证前额叶活动与情绪刺激期间面部皮肤血流量变化呈正相关的假设，我们检测了14名受试者在情绪刺激视听挑战(通过观看喜剧、风景和恐怖电影)2分钟期间，前额叶氧合(用近红外光谱)和面部皮肤血流量(用二维激光散斑和多普勒血流计)的动态变化。同时测定手部皮肤血流量和全身血流动力学。每个情绪刺激的愉悦程度和意识程度通过主观评分从−5(最不愉快；最无意识)到+5(最愉快；最有意识)来估计。带正电的情绪刺激(喜剧)同时减少(P<0.05)前额叶供氧和面部皮肤血流量，而带负电的(恐怖)或中性(风景)情绪刺激不会改变或轻微减少它们。在带正电的情绪刺激过程中，手部皮肤血流量和全身心血管变量的任何一个都没有显著变化。在不改变灌流压力的情况下，前额叶血氧变化与面部皮肤血流量变化呈高度正相关，与主观愉悦感评分呈负相关。在正电情绪刺激下，前额叶供氧能力下降，表明前额叶神经活动减少，进而可能引发神经介导的面部皮肤血管收缩。
Our laboratory reported that facial skin blood flow may serve as a sensitive tool to assess an emotional status. Cerebral neural correlates during emotional interventions should be sought in relation to the changes in facial skin blood flow. To test the hypothesis that prefrontal activity has positive relation to the changes in facial skin blood flow during emotionally charged stimulation, we examined the dynamic changes in prefrontal oxygenation (with near‐infrared spectroscopy) and facial skin blood flows (with two‐dimensional laser speckle and Doppler flowmetry) during emotionally charged audiovisual challenges for 2 min (by viewing comedy, landscape, and horror movie) in 14 subjects. Hand skin blood flow and systemic hemodynamics were simultaneously measured. The extents of pleasantness and consciousness for each emotional stimulus were estimated by subjective rating from −5 (the most unpleasant; the most unconscious) to +5 (the most pleasant; the most conscious). Positively charged emotional stimulation (comedy) simultaneously decreased (P < 0.05) prefrontal oxygenation and facial skin blood flow, whereas negatively charged (horror) or neutral (landscape) emotional stimulation did not alter or slightly decreased them. Any of hand skin blood flow and systemic cardiovascular variables did not change significantly during positively charged emotional stimulation. The changes in prefrontal oxygenation had a highly positive correlation with the changes in facial skin blood flow without altering perfusion pressure, and they were inversely correlated with the subjective rating of pleasantness. The reduction in prefrontal oxygenation during positively charged emotional stimulation suggests a decrease in prefrontal neural activity, which may in turn elicit neurally mediated vasoconstriction of facial skin blood vessels.