The effects of peptides on partner preference formation are predicted by habitat in prairie voles
The effects of peptides on partner preference formation are predicted by habitat in prairie voles
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DOI：
10.1006/hbeh.2000.1633
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发表时间：
2001-02-01
影响因子：
3.5
通讯作者：
Carter, CS
中科院分区：
文献类型：
--
作者：
Cushing, BS;Martin, JO;Carter, CS
这项研究检验了这样一个假设：交配系统的种内变异与外周精氨酸加压素 (AVP) 促进伴侣偏好的能力差异相关。据推测，环境条件的差异（堪萨斯州比伊利诺伊州更干旱）是造成堪萨斯州（KN）和伊利诺伊州（IL）草原田鼠交配系统中一些种内差异的原因。我们预测来自 KN 的草原田鼠对外周 AVP 的行为比来自 IL 的草原田鼠更敏感。为了检验这一假设，实验室饲养的 60 至 120 天的雄性和雌性、来自 KN 和 IL 的草原田鼠接受了 3 次 AVP 或等渗盐水的皮下注射。然后将动物与指定为“伴侣”的成年异性成员放置在一起，进行 1 小时的同居，随后测试其对熟悉伴侣和类似陌生人的偏好。只有接受 AVP 治疗的 KN 雄性表现出对伴侣的显着偏好。使用相同的实验范式，我们还检查了外周催产素 (OT) 促进 KN 草原田鼠伴侣偏好的能力。 OT 促进了女性的伴侣偏好，但没有促进男性。这一发现与之前描述外周 OT 对 IL 草原田鼠的影响的结果一致。我们还检验了以下假设：KN 和 IL 雄性的差异反应与 AVP (V-1a) 受体分布的差异有关。然而，KN 和 IL 雄性之间 V-1a 受体的分布没有明显差异。这项研究的结果表明，草原田鼠的社会行为调节存在种内和两性之间的变异。此外，这些发现表明，种内变异的直接原因可以通过对起源栖息地的了解来预测。 (C) 2001 年学术出版社。
This study tested the hypothesis that intraspecific variations in mating systems are correlated with differences in the capacity of peripheral arginine vasopressin (AVP) to facilitate partner preferences. It has been hypothesized that differences in environmental conditions, Kansas being more xeric than Illinois, are responsible for some of the intraspecific differences in the mating systems between Kansas (KN) and Illinois (IL) prairie voles. We predicted that prairie voles from KN would be more behaviorally sensitive to peripheral AVP than prairie voles from IL. To test this hypothesis 60- to 120-day-old male and female, lab-reared, prairie voles originating from KN and IL received three subcutaneous injections of AVP or isotonic saline. Animals were then placed with an adult member of the opposite sex, designated a "partner," for a 1-hour period of cohabitation and subsequently tested for preference for the familiar partner Versus a comparable stranger. Only KN males treated with AVP displayed a significant preference for the partner. Using the same experimental paradigm we also examined the ability of peripheral oxytocin (OT) to facilitate partner preference in KN prairie voles. OT facilitated partner preference in females, but not males. This finding was consistent with previous results describing the effects of peripheral OT in IL prairie voles. We also examined the hypothesis that the differential response of KN and IL males would be associated with differences in the distribution of AVP (V-1a) receptors. However, there was no apparent difference in the distribution of V-1a receptors between KN and IL males. The results of this study indicate that there is both intraspecific and intersexual variation in the regulation of social behavior in prairie voles. In addition, these findings suggest that the proximate causes of intraspecific variation may be predicted by knowledge of the habitat of origin. (C) 2001 Academic Press.