Distribution of fim3 and flaA TTGE sequence types amongst isolates of Bordetella bronchiseptica from different host animals.
Distribution of fim3 and flaA TTGE sequence types amongst isolates of Bordetella bronchiseptica from different host animals.
复制标题
来自不同宿主动物的支气管败血博德特氏菌分离株中 fim3 和 flaA TTGE 序列类型的分布。
DOI：
10.1099/0022-1317-51-7-557
复制
发表时间：
2002
影响因子：
3
通讯作者：
C. Winstanley
中科院分区：
文献类型：
--
作者：
A. Shina;C. Hart;Matthew D Stenton;S. Dawson;C. McCracken;S. Binns;R. Gaskell;C. Winstanley
采用时间温度梯度凝胶电泳（TTGE）对不同动物宿主的支气管败血波氏杆菌分离株进行fim 3和flaA基因分型。所有来自猫（n = 138）、狗（n = 42）和猪（n = 13）的分离株可分别归属于两种fim 3和三种flaA TTGE序列类型之一。两个鸟类分离株和一个绒猴分离株表现出新的fim 3序列类型。在犬和猪的分离株中，fim 3（分别为87.5%和100%的分离株为优势型）和flaA（分别为95%和92%的分离株为优势型）的TTGE序列类型明显不同。有一个更广泛的分布之间的猫分离物的TTGE序列类型。由于菌毛和鞭毛都参与了博德特氏菌对宿主细胞的粘附，因此菌毛蛋白和FlaA的序列变异可能在宿主偏好中发挥作用。
Isolates of Bordetella bronchiseptica associated with different animal hosts were analysed by fim3 and flaA genotyping by temporal temperature gradient gel electrophoresis (TTGE). All the isolates from cats (n = 138), dogs (n = 42) and pigs (n = 13) could be assigned to one of two fim3 and one of three flaA TTGE sequence types, respectively. Two avian isolates and a marmoset isolate exhibited novel fim3 sequence types. Dominant but different TTGE sequence types were apparent in isolates from dogs and pigs for both fim3 (87.5% and 100%, respectively, of isolates were the dominant type) and flaA (95% and 92%, respectively, of isolates were the dominant type). There was a wider distribution of TTGE sequence types amongst cat isolates. As both fimbriae and flagella have been implicated in adherence of bordetellae to host cells, sequence variations in fimbrial proteins and FlaA may have a role to play in host preferences.
影响因子：
158.5
作者：
Gustafsson, L;Hallander, HO;Storsaeter, J
通讯作者：
Storsaeter, J