The relationship between systolic vector flow mapping parameters and left ventricular cardiac function in healthy dogs
The relationship between systolic vector flow mapping parameters and left ventricular cardiac function in healthy dogs
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DOI：
10.1007/s00380-017-1093-1
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发表时间：
2018-05-01
影响因子：
1.5
通讯作者：
Tanaka, Ryou
中科院分区：
文献类型：
--
作者：
Goya, Seijirow;Wada, Tomoki;Tanaka, Ryou
矢量流标测（VFM）是一种新的超声心动图技术，它显示了血流矢量和涡流，使左心室内的血流动力学评价成为可能。VFM提供了几个独特的参数：环流，涡度，涡面积和能量损失。本研究旨在揭示VFM参数与心功能的关系。将5只健康Beagle犬麻醉并给予多巴酚丁胺（0、2、4、8、12 μ g/kg/min）。采用压力-容积传导导管测量心功能，获得压力-容积图。使用VFM测量了系统最大环流、涡度、涡面积和能量损失。多巴酚丁胺可增加收缩期最大循环、收缩期涡度、收缩期涡面积和收缩期能量损失。收缩期最大循环与射血分数（r = 0.76）、最大正左心室（LV）压力导数（dP/dt max）（r = 0.80）和收缩末期LV弹性（r = 0.73）之间存在显著相关性。收缩期涡度和收缩期涡面积分别与射血分数（r = 0.76，0.68）、dP/dt max（r = 0.76，0.69）和收缩末期左室弹性（r = 0.62，0.74）密切相关。收缩期能量损失与dP/dt max（r = 0.78）、收缩期最大循环（r = 0.81）和收缩期涡度（r = 0.82）密切相关。目前的研究表明，收缩VFM参数与左室收缩力。此外，收缩期能量损失易受收缩期涡度和收缩期最大循环等收缩期涡参数的影响。SYSTEM-VFM参数是反映左心室收缩力的新的流体动力学指标。
Vector flow mapping (VFM) is a novel echocardiographic technology that shows blood flow vectors and vortexes, enabled the hydrokinetic evaluation of hemodynamics within the left ventricle. VFM provides several unique parameters: circulation, vorticity, vortex area, and energy loss. The present study aims to reveal a relationship between VFM parameters and cardiac function. Five healthy Beagle dogs were anesthetized and administered with dobutamine (0, 2, 4, 8, 12 A mu g/kg/min). Pressure-volume diagrams were acquired to assess cardiac function using pressure-volume conductance catheter. Systolic maximum circulation, vorticity, vortex area, and energy loss were measured using VFM. The systolic maximum circulation, systolic vorticity, systolic vortex area, and systolic energy loss were increased by dobutamine administration. There was a strongly significant correlation between the systolic maximum circulation and ejection fraction (r = 0.76), maximal positive left ventricular (LV) pressure derivatives (dP/dt max) (r = 0.80), and end-systolic LV elastance (r = 0.73). Systolic vorticity and systolic vortex area were strongly correlated with ejection fraction (r = 0.76, 0.68) and dP/dt max (r = 0.76, 0.69), and end-systolic LV elastance (r = 0.62, 0.74), respectively. Systolic energy loss was strongly correlated with dP/dt max (r = 0.78), systolic maximum circulation (r = 0.81), and systolic vorticity (r = 0.82). The present study revealed that systolic VFM parameters are associated with the LV contractility. Furthermore, systolic energy loss was susceptible to the systolic vortex parameters such as systolic vorticity and systolic maximum circulation. Systolic VFM parameters are new hydrokinetic indices reflecting LV contractility.