Cancer disparities between mainland and island Puerto Ricans
Cancer disparities between mainland and island Puerto Ricans
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DOI：
10.1590/s1020-49892009000500003
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发表时间：
2009-05-01
期刊：
影响因子：
--
通讯作者：
Rohan, Thomas E.
中科院分区：
文献类型：
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作者：
Ho, Gloria Y. F.;Figueroa-Vallés, Nayda R.;Rohan, Thomas E.
目标。检查单个拉美裔亚群-波多黎各人-的癌症发病率，并比较居住在美国的波多黎各大陆人、波多黎各岛上的波多黎各人和美国非西班牙裔白人的发病率，以揭示波多黎各特定种族的癌症模式和差异。发病率数据来自波多黎各和波多黎各大陆人口密度高的美国东北部三个州(纽约州、新泽西州和康涅狄格州)的癌症登记。年龄调整率采用标准化比率(SRR)进行比较。波多黎各岛民的总癌症发病率最低，波多黎各大陆人居中，美国非西班牙裔白人最高。与波多黎各大陆人相比，岛上居民的主要癌症--肺癌(男性为0.36，女性为0.29)、前列腺癌(SRR=0.71)、女性乳腺癌(SRR=0.73)和结直肠癌(男性为0.74，女性为0.65)--以及几种不太常见的癌症(膀胱癌、非霍奇金淋巴瘤、肝、肾和肾盂、胰腺、甲状腺、白血病和皮肤黑色素瘤)的发病率(p<；0.05)明显较低。波多黎各大陆人的总体癌症发病率略低于美国非西班牙裔白人，但波多黎各大陆人的胃癌、肝癌和宫颈癌的发病率在这三个人群中最高。尽管波多黎各在社会经济上处于不利地位，但岛上的波多黎各人的癌症发病率相对较低。确定致癌因素将为癌症研究提供信息，了解大陆同行癌症风险增加的原因将有助于制定针对种族的干预计划。
Objectives. Examination of cancer rates in a single Hispanic subgroup-Puerto Ricans- and comparison of incidence rates among mainland Puerto Ricans living in the United States, island Puerto Ricans in Puerto Rico, and U. S. non-Hispanic whites to reveal ethnic-specific cancer patterns and disparities in Puerto Ricans.Methods. Incidence data were obtained from the cancer registries of Puerto Rico and three U. S. northeastern states (New York, New Jersey, and Connecticut) with a high density of mainland Puerto Ricans. Age-adjusted rates were compared by standardized rate ratios (SRRs).Results. Total cancer incidence was the lowest in island Puerto Ricans, intermediate for mainland Puerto Ricans, and highest in U. S. non-Hispanic whites. Compared to mainland Puerto Ricans, islanders had significantly lower rates (p < 0.05) for major cancers-lung (SRRs = 0.36 in males and 0.29 in females), prostate (SRR = 0.71), female breast (SRR = 0.73), and colon-rectum (SRRs = 0.74 in males and 0.65 in females)-as well as several less common cancers (urinary bladder; non-Hodgkin lymphoma; liver; kidney and renal pelvis; pancreas; thyroid; leukemia; and skin melanoma). Overall cancer rates in mainland Puerto Ricans were modestly lower than those in U. S. non-Hispanic whites, but mainland Puerto Ricans had the highest rates for stomach, liver, and cervical cancers among the three populations.Conclusion. Despite socioeconomic disadvantages, island Puerto Ricans have relatively low cancer incidence. Identifying contributing factors would be informative for cancer research, and understanding the reasons for increased cancer risk in their mainland counterparts would facilitate the development of ethnic-specific intervention programs.