A large-scale validation study of the medication adherence rating scale (MARS)
A large-scale validation study of the medication adherence rating scale (MARS)
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DOI：
10.1016/j.schres.2007.10.029
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发表时间：
2008-03-01
影响因子：
4.5
通讯作者：
Freeman, Daniel
中科院分区：
文献类型：
--
作者：
Fialko, Laura;Garety, Philippa A.;Freeman, Daniel
药物依从性是精神病病程和预后的重要预测指标。药物依从性评定量表（MARS）是一种精神病患者药物依从性的十项自我报告量表[Thompson， K, Kulkarni， J, Sergejew, a.a., 2000]。一种新的精神病药物依从性评定量表（MARS）的信度和效度。精神分裂症研究。241 - 247年)。虽然初步结果表明量表具有良好的信度和效度，但开发样本较小。目前的研究旨在在一个四倍大的样本中建立MARS的心理测量特性。该量表对277名精神病患者进行了调查，同时对他们的洞察力和精神病理学进行了测量。药物依从性由每个人的关键工作者独立评估。结果表明，MARS的内部一致性虽然足够，但比原始样品低。MARS总分与关键员工依从性的相关性较弱，因此量表的并发效度仅为中至弱。复制了MARS的三因子结构。对因子得分的检查表明，因子I总分，对应于药物依从性问卷[Morisky，D.E.、绿色、l莱文,D.M., 1986年。药物依从性自我报告测量的并发性和预测性效度。医疗保健[24,67 -74]可能是衡量药物依从性行为比总量表得分更可取的指标。(C) 2007 Elsevier B.V.版权所有
Adherence to medication is an important predictor of illness course and outcome in psychosis. The Medication Adherence Rating Scale (MARS) is a ten-item self-report measure of medication adherence in psychosis [Thompson, K., Kulkarni, J., Sergejew, A.A., 2000. Reliability and validity of a new Medication Adherence Rating Scale (MARS) for the psychoses. Schizophrenia Research. 42. 241-247]. Although initial results suggested that the scale has good reliability and validity, the development sample was small. The current study aimed to establish the psychometric properties of the MARS in a sample over four times larger. The scale was administered to 277 individuals with psychosis, along with measures of insight and psychopathology. Medication adherence was independently rated by each individual's keyworker. Results showed the internal consistency of the MARS to be lower than in the original sample, though adequate. MARS total score correlated weakly with keyworker-rated adherence, hence concurrent validity of the scale appeared only moderate to weak. The three factor structure of the MARS was replicated. Examination of the factor scores suggested that the factor I total score, which corresponds to the Medication Adherence Questionnaire [Morisky,D.E., Green,L.W. and Levine,D.M., 1986. Concurrent and predictive validity of a self-reported measure of medication adherence. Medical Care. 24, 67-74] may be a preferable measure of medication adherence behaviour to the total scale score. (C) 2007 Elsevier B.V. All rights reserved.