New stereoselective entry to azaspirocyclic nucleus of halichlorine and pinnaic acids by radical translocation/cyclization reaction
New stereoselective entry to azaspirocyclic nucleus of halichlorine and pinnaic acids by radical translocation/cyclization reaction
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DOI：
10.1021/ol034942v
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发表时间：
2003-08-21
期刊：
影响因子：
5.2
通讯作者：
Ihara, M
中科院分区：
文献类型：
--
作者：
Takasu, K;Ohsato, H;Ihara, M
从一种哌啶类化合物开始，发展了一种立体选择性的方法来研究卤化氯和品甲酸的螺旋环核。这一序列中的一个关键转换涉及级联的自由基转位/环化过程。
graphicA stereoselective approach to the spirocyclic nucleus of halichlorine and pinnaic acids has been developed starting from a piperidine derivative. A key transformation in this sequence involves a cascade radical trans location/cyclization process.