Prediction of strength and strain of the proximal femur by a CT-based finite element method
Prediction of strength and strain of the proximal femur by a CT-based finite element method
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DOI：
10.1016/j.jbiomech.2006.08.003
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发表时间：
2007-01-01
影响因子：
2.4
通讯作者：
Nakamura, Kozo
中科院分区：
文献类型：
--
作者：
Bessho, Masahiko;Ohnishi, Isao;Nakamura, Kozo
髋部骨折是骨质疏松症最严重的并发症，已被认为是一个重大的公共卫生问题。在老年人中。髋部骨折的发生是由于骨质疏松导致股骨近端脆性增加的结果。准确量化股骨近端强度是评估骨折风险和制定预防措施的必要条件。基于ct的有限元分析可能实现股骨近端强度的精确评估。本研究的目的是利用ct有限元法建立一个能够准确预测股骨近端强度和表面应变的模拟模型，并通过新鲜冷冻尸体标本的载荷试验验证模型的准确性。收集11根右股骨。使用校准模体获得股骨近端轴向CT扫描，并以此构建三维有限元模型。进行了材料非线性有限元分析。计算了屈服载荷和断裂载荷，确定了构件失效位置和主应变分布。应变片附着于股骨近端表面。对每根股骨进行准静态压缩试验。预测的屈服载荷、断裂载荷和主应变与实测值呈显著相关（r = 0.941, 0.979, 0.963）。有限元分析结果表明，受压破坏的实体单元和壳单元位于与试验断裂部位相同的亚capital区域。(C) 2006 Elsevier Ltd版权所有。
Hip fractures are the most serious complication of osteoporosis and have been recognized as a major public health problem. In elderly persons. hip fractures occur as a result of increased fragility of the proximal femur due to osteoporosis. It is essential to precisely quantify the strength of the proximal femur in order to estimate the fracture risk and plan preventive interventions. CT-based finite element analysis could possibly achieve precise assessment of the strength of the proximal femur. The purpose of this study was to create a simulation model that could accurately predict the strength and surface strains of the proximal femur using a CT-based finite element method and to verify the accuracy of our model by load testing using fresh frozen cadaver specimens. Eleven right femora were collected. The axial CT scans of the proximal femora were obtained with a calibration phantom, from which the 3D finite element models were constructed. Materially nonlinear finite element analyses were performed. The yield and fracture loads were calculated, while the sites where elements failed and the distributions of the principal strains were determined.The strain gauges were attached to the proximal femoral surfaces. A quasi-static compression test of each femur was conducted. The yield loads, fracture loads and principal strains of the prediction significantly correlated with those measured (r = 0.941, 0.979, 0.963). Finite element analysis showed that the solid elements and shell elements in undergoing compressive failure were at the same subcapital region as the experimental fracture site. (C) 2006 Elsevier Ltd. All rights reserved.