Chronic diseases in pregnant women: prevalence and birth outcomes based on the SNiP-study
Chronic diseases in pregnant women: prevalence and birth outcomes based on the SNiP-study
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DOI：
10.1186/1471-2393-14-75
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发表时间：
2014-02-19
影响因子：
3.1
通讯作者：
Thyrian, Jochen Rene
中科院分区：
文献类型：
--
作者：
Kersten, Ines;Lange, Anja Erika;Thyrian, Jochen Rene
背景：“妊娠与疾病”这一主题对于产妇的健康和新生儿的结局尤为重要。国际文献集中于妊娠期间的急性疾病;然而，只有少数研究调查孕妇的慢性疾病。这项研究的重点是与怀孕无关的育龄妇女疾病。该文件的目的是提供人口为基础的慢性疾病的患病率在育龄妇女和比较两组慢性病妇女和健康妇女的详细社会人口学，围产期和产前参数和birth outcomes.Methods：数据n = 5320育龄妇女进行了评估的背景下，以人口为基础的调查波美拉尼亚的新生儿（SNiP）。数据是通过面对面的访谈，自我应用的问卷调查，并从分娩时的医疗记录摘要。评估了社会人口和健康状况数据，包括从医疗记录中删除的慢性疾病。一套全面的产前和围产期variaibles进行了assessed.Results：在SNiP，每五个孕妇患有至少一种慢性疾病，和较高的患病率已在文献中报道。慢性病妇女与健康妇女在年龄、文化程度和收入方面存在显著差异。产前并发症在健康组比慢性病组更常见。慢性病妇女剖宫产率高于健康妇女。每10名妇女至少有一种慢性疾病生下了早产儿，而只有一个在每13名妇女在健康对照组生下了早产儿。结论：这项分析是第一个以人口为基础的研究中，所有的慢性疾病可以考虑。SNiP数据中基于人群的患病率始终低于文献中的患病率。慢性病妇女和健康妇女在围产期和产前变量以及人口水平上的出生结局方面存在差异。然而，它们的发生率低于预期，需要进一步分析，重点是具体疾病。
Background: The subject of "pregnancy and disease" is of particular importance for maternal well-being and neonatal outcomes. The international literature has focused on acute diseases during pregnancy; however, there are only a few studies investigating chronic diseases in pregnant women. The focus of this study is on diseases of women in childbearing age that are not related to the pregnancy. The objective of the paper is to deliver population based prevalences of chronic dieases in childbearing women and compare the two groups of chronically ill women and healthy women in detail regarding sociodemography, peri-and prenatal parameters and birth outcomes.Methods: Data of n = 5320 childbearing women were evaluated in the context of the population-based Survey of Neonates in Pomerania (SNiP). Data were obtained via face-to-face interviews, self-applied questionnaires, and abstraction from medical records at the time of giving birth. Sociodemographic and health status data were assessed, including chronic diseases that were taken out of medical records. A comprehensive set of pre- and perinatal varaiables were assessed.Results: In the SNiP, every fifth pregnant woman suffers from at least one chronic disease, and higher prevalence rates have been reported in the literature. There was a significant difference between chronically ill women and healthy women in age, education and income. Prenatal complications were more frequent in the healthy group than in the chronic disease group. Women with chronic diseases delivered by Cesarean section more frequently than women in the healthy group. Every tenth woman with at least one chronic disease gave birth to a premature infant, while only one in every 13 woman in the healthy control group gave birth to a premature infant.Conclusions: This analysis is the first population-based study in which all chronic diseases could be taken into consideration. The population-based prevalences rates in the SNiP data are consistently lower than those found in the literature. There are differences between chronically ill women and healthy women in peri-and prenatal variables as well as birth outcome on the population level. However, they are less frequent than expected and further analyses are need focusing on specific diseases.