Does dampness and mold in schools affect health? Results of a meta-analysis
Does dampness and mold in schools affect health? Results of a meta-analysis
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DOI：
10.1111/ina.12588
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发表时间：
2019-08-05
期刊：
影响因子：
5.8
通讯作者：
Johnson, Alexandra L.
中科院分区：
文献类型：
--
作者：
Fisk, William J.;Chan, Wanyu R.;Johnson, Alexandra L.
本文对已发表的有关明显潮湿、水渍、可见霉菌和/或霉菌气味的学校居住者呼吸健康的研究结果进行了荟萃分析。使用随机效应模型对呼吸系统健康影响与学校潮湿和霉菌之间的关联进行集中估计和置信限。荟萃分析中纳入了 11 项研究，全部采用横断面设计；然而，对某些健康结果的分析仅基于四项研究。使用成人和儿童的综合数据、仅使用儿童的数据以及排除两项研究后使用成人和儿童的数据进行分析。荟萃分析对比值比的中心估计值始终高于统一值。咳嗽和喘息对健康产生不良影响的证据最为明显，其置信度有限，排除了部分或全部分析的统一性。咳嗽的比值比为 1.32，喘息的比值比为 1.68，表明健康风险适度增加。荟萃分析中未包含的研究提供了额外的证据，表明学校的潮湿和霉菌与不良健康结果相关。这些荟萃分析和荟萃分析中未包含的已发表文献表明，学校的潮湿和霉菌与呼吸道健康的不良影响有关。
This paper provides meta-analyses of the published findings relating the respiratory health of occupants of schools with visible dampness, water damage, visible mold, and/or mold odor. Random effects models were used to develop central estimates and confidence limits for the associations of respiratory health effects with school dampness and mold. Eleven studies, all with cross-sectional designs, were included in the meta-analyses; however, analyses for some health outcomes were based on as few as four studies. Analyses were performed using data from adults and children combined, using only data from children, and using data from adults and children after excluding two studies. The central estimates of odds ratios from the meta-analyses were consistently above unity. The evidence of adverse health effects was strongest for cough and wheeze, which had confidence limits excluding unity in some or all analyses. The odds ratios of 1.32 for cough and 1.68 for wheeze suggest moderate increases in health risk. Studies not included in the meta-analyses provide additional evidence that dampness and mold in schools are associated with adverse health outcomes. These meta-analyses and the published literature not included in the meta-analyses suggest that dampness and mold in schools are associated with adverse respiratory health effects.