MOLECULAR AND ISOTOPIC ANALYSES OF THE HYDROXY-ACIDS, DICARBOXYLIC-ACIDS, AND HYDROXYDICARBOXYLIC ACIDS OF THE MURCHISON METEORITE
MOLECULAR AND ISOTOPIC ANALYSES OF THE HYDROXY-ACIDS, DICARBOXYLIC-ACIDS, AND HYDROXYDICARBOXYLIC ACIDS OF THE MURCHISON METEORITE
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DOI：
10.1016/0016-7037(93)90197-5
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发表时间：
1993-10-01
影响因子：
5
通讯作者：
KRISHNAMURTHY, RV
中科院分区：
文献类型：
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作者：
CRONIN, JR;PIZZARELLO, S;KRISHNAMURTHY, RV
使用气相色谱-质谱联用技术对默奇森陨石中的羟基单羧酸、二羧酸和羟基二羧酸进行了叔丁基二甲基甲硅烷基衍生物分析。此前在陨石中尚未发现羟基二羧酸。每类化合物的碳链最多为 C-8 或 C-9，并且每个碳数代表许多（如果不是全部）链和取代位置异构体。 α-羟基羧酸和α-羟基二羧酸在结构上对应于许多已知的陨石α-氨基羧酸和α-氨基二羧酸，这一事实支持了Strecker合成参与两类化合物的形成的提议。同位素分析表明，这些酸与预期的陆地有机化合物相比更丰富：然而，就碳和氢而言，羟基酸的同位素似乎比氨基酸轻。如果这两类化合物完全来自共同的前体，就像 Strecker 合成的情况一样，则不会预期后一个发现。
The hydroxymonocarboxylic acids, dicarboxylic acids, and hydroxydicarboxylic acids of the Murchison meteorite were analyzed as their tert-butyldimethylsilyl derivatives using combined gas chromatography-mass spectrometry. The hydroxydicarboxylic acids have not been found previously in meteorites. Each class of compounds is numerous with carbon chains up to C-8 or C-9 and many, if not all, chain and substitution position isomers represented at each carbon number. The alpha-hydroxycarboxylic acids and alpha-hydroxydicarboxylic acids correspond structurally to many of the known meteoritic alpha-aminocarboxylic acids and alpha-aminodicarboxylic acids, a fact that supports the proposal that a Strecker synthesis was involved in the formation of both classes of compounds. Isotopic analyses show these acids to be Drich relative to terrestrial' organic compounds as expected: however, the hydroxy acids appear to be isotopically lighter than the amino acids with respect to both carbon and hydrogen. The latter finding would not be expected if both classes of compounds came exclusively from common precursors as would have been the case for a Strecker synthesis.