Chitosan-coated organosilica nanoparticles as a dual responsive delivery system of natural fragrance for axillary odor problem
Chitosan-coated organosilica nanoparticles as a dual responsive delivery system of natural fragrance for axillary odor problem
复制标题
壳聚糖包被的有机二氧化硅纳米粒子作为天然香料的双重响应传递系统，用于解决腋臭问题
DOI：
10.1016/j.carbpol.2021.118277
复制
发表时间：
2021
影响因子：
11.2
通讯作者：
Chen Kunlin
中科院分区：
文献类型：
--
作者：
Hu Jing;Zhang Jianlei;Li Lin;Bao Xiaoli;Deng Weijun;Chen Kunlin
Citronellol (CI)-loaded, chitosan (CS)-enclosed dendritic mesoporous organosilica nanoparticles (CI@D-MONs@CS) are successfully fabricated. The synthesized CI@D-MONs@CS present spherical shape with the particle size of 424±24 nm in diameter and dendritic mesopores. CI loading ratio of CI@D-MONs@CS is about 12.42% from TGA analysis. CI release from CI@D-MONs@CS exhibits pH-redox dual responsiveness. More interesting, the axillary deodorant effect is investigated withStaphylococcus haemolyticusin an artificial sweat model. The results show that CI@D-MONs@CS present an excellent bacteria-killing effect and the smell of artificial sweat is greatly improved, avoiding the formation of undesirable odorant compounds from the bacteria. The obtained CI@D-MONs@CS is a potential carrier of natural fragrance or actives with dual responsive release. The application of CI@D-MONs@CS is a new and effective strategy to the axillary odor problem.
