Na+ more strongly inhibits DNA compaction by spermidine (3+) than K+
Na+ more strongly inhibits DNA compaction by spermidine (3+) than K+
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DOI：
10.1016/j.cplett.2006.05.120
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发表时间：
2006-08-04
影响因子：
2.8
通讯作者：
Yoshikawa, Kenichi
中科院分区：
文献类型：
--
作者：
Hibino, Kumiko;Yoshikawa, Yuko;Yoshikawa, Kenichi
采用单分子观察方法研究了碱金属离子（Li+、Na+、K+、Rb+和Cs+）对亚精胺诱导的DNA压缩的保护作用。我们发现，所有的碱金属盐防止DNA压缩，其中Na+更强烈地防止DNA压缩比其他碱金属离子。我们讨论了我们的结果在离子半径的变化有关的净平移熵的小离子由于三价和一价阳离子之间的离子交换。(c)2006 Elsevier B.V.保留所有权利。
The protective effects of alkali metal ions (Li+, Na+, K+, Rb+ and Cs+) against spermidine-induced DNA compaction were studied using single-molecule observations. We found that all alkali metal salts prevent DNA compaction, where Na+ more strongly prevented DNA compaction than other alkali metal ions. We discuss our results in terms of changes in ionic radii in relation to the net translational entropy of small ions due to ionic exchange between trivalent and monovalent cations. (c) 2006 Elsevier B.V. All rights reserved.