Evaluation of Esophageal Motility Utilizing the Functional Lumen Imaging Probe
Evaluation of Esophageal Motility Utilizing the Functional Lumen Imaging Probe
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DOI：
10.1038/ajg.2016.454
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发表时间：
2016-12-01
影响因子：
9.8
通讯作者：
Pandolfino, John E.
中科院分区：
文献类型：
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作者：
Carlson, Dustin A.;Kahrilas, Peter J.;Pandolfino, John E.
目的：在镇静上消化道内窥镜检查期间，可以使用功能性管腔成像探针（FLIP）评估食管胃连接部（EGJ）的扩张性和扩张介导的蠕动。我们的目的是描述使用 FLIP 地形图对吞咽困难患者进行食管动力评估。 方法：总共纳入了 145 名吞咽困难患者（年龄 18-85 岁，54% 女性），他们使用 16 厘米 FLIP 组件和高分辨率测压 (HRM) 完成了上消化道内窥镜检查。根据食管运动障碍芝加哥分类对 HRM 进行分析；主要的食管运动障碍被认为是“异常”。使用定制程序对 FLIP 研究进行分析，以计算 EGJ 扩张指数 (DI) 并生成 FLIP 地形图来识别食管收缩模式。如果 EGJ-DI 为 FLIP 地形，则认为 FLIP 地形“异常”
OBJECTIVES: Esophagogastric junction (EGJ) distensibility and distension-mediated peristalsis can be assessed with the functional lumen imaging probe (FLIP) during a sedated upper endoscopy. We aimed to describe esophageal motility assessment using FLIP topography in patients presenting with dysphagia.METHODS: In all, 145 patients (aged 18-85 years, 54% female) with dysphagia that completed upper endoscopy with a 16-cm FLIP assembly and high-resolution manometry (HRM) were included. HRM was analyzed according to the Chicago Classification of esophageal motility disorders; major esophageal motility disorders were considered "abnormal". FLIP studies were analyzed using a customized program to calculate the EGJ-distensibility index (DI) and generate FLIP topography plots to identify esophageal contractility patterns. FLIP topography was considered "abnormal" if EGJ-DI was