Alcohol intake and sickness absence:: A curvilinear relation
Alcohol intake and sickness absence:: A curvilinear relation
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DOI：
10.1093/aje/kwf138
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发表时间：
2002-11-15
影响因子：
5
通讯作者：
Pentti, J
中科院分区：
文献类型：
--
作者：
Vahtera, J;Poikolainen, K;Pentti, J
除了与心血管疾病有关的发现外，人们对酒精摄入量与健康之间的U形关系知之甚少。经医疗证明的病假是一项健康指标，其中冠心病只是一个次要因素。为了调查饮酒与病假之间的关系，对芬兰1 490名男性和4 952名女性市政雇员的4年（1997-2000年）医疗证明病假记录进行了评估。分层泊松回归，调整自我报告的行为和生物危险因素，心理社会危险因素，和心血管疾病，被用来估计率比及其95%的置信区间，有关病假的每一个级别的饮酒量。对于男性和女性来说，平均每周饮酒量和病假之间存在显着的曲线趋势。与轻度饮酒者相比，从未饮酒者、前饮酒者和重度饮酒者的经医学证明的病假缺勤率高1.2倍（95%置信区间：1.1，1.3）。酒精摄入量和健康之间的U形关系不太可能被解释为由于心理社会差异或将以前的饮酒者纳入非饮酒者类别而造成的混淆。适量饮酒还可以减少心血管疾病以外的健康问题。
Little is known about the U-shaped relation between alcohol intake and health beyond findings related to cardiovascular disease. Medically certified sickness absence is a health indicator in which coronary heart disease is only a minor factor. To investigate the relation between alcohol intake and sickness absence, records regarding medically certified sick leaves from all causes were assessed for 4 years (1997-2000) in a cohort of 1,490 male and 4,952 female municipal employees in Finland. Hierarchical Poisson regression, adjusted for self-reported behavioral and biologic risk factors, psychosocial risk factors, and cardiovascular diseases, was used to estimate the rate ratios and their 95% confidence intervals, relating sickness absence to each level of alcohol consumption. For both men and women, a significant curvilinear trend was found between level of average weekly alcohol consumption and sickness absence. The rates of medically certified sickness absence were 1.2-fold higher (95% confidence interval: 1.1, 1.3) for never, former, and heavy drinkers compared with light drinkers. The U-shaped relation between alcohol intake and health is not likely to be explained by confounding due to psychosocial differences or inclusion of former drinkers in the nondrinkers category. Moderate alcohol consumption also may reduce health problems other than cardiovascular disease.