Glucose, insulin and somatostatin infusion for the determination of insulin sensitivity.
Glucose, insulin and somatostatin infusion for the determination of insulin sensitivity.
复制标题
葡萄糖、胰岛素和生长抑素输注用于测定胰岛素敏感性。
DOI：
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发表时间：
1977
影响因子：
5.8
通讯作者：
Hiroshi Abe
中科院分区：
文献类型：
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作者：
Y. Harano;S. Ohgaku;H. Hidaka;K. Haneda;R. Kikkawa;Yukio Shigeta;Hiroshi Abe
Glucose, insulin and somatostatin infusion over 2 hours effectively suppressed endogenous secretion of insulin, glucagon and growth hormones. Steady state plasma glucose level (SSPG) which should be inversely proportional to insulin sensitivity was obtained. In 6 adult-onset non-obese untreated diabetics, mean value of insulin sensitivity indices was significantly reduced compared with normal. In 5 insulin-treated diabetics and in 5 subjects with borderline glucose tolerance including 2 obese subjects, insulin sensitivity for glucose utilization was also significantly diminished.
