Trends in self-poisoning and psychotropic drug use in people aged 5-19 years: a population-based retrospective cohort study in Australia

Trends in self-poisoning and psychotropic drug use in people aged 5-19 years: a population-based retrospective cohort study in Australia
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DOI:
10.1136/bmjopen-2018-026001
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发表时间:
2019-06-01
期刊:
影响因子:
2.9
通讯作者:
Buckley, Nicholas A.
Buckley, Nicholas A.
中科院分区:
医学3区
文献类型:
--
作者:
Cairns, Rose;Karanges, Emily A.;Buckley, Nicholas A.

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目的了解澳大利亚年轻人自我中毒和精神药物使用的趋势。设计以人群为基础的回顾性队列研究。设置新南威尔士州和维多利亚州毒物信息中心的电话(2006-2016年,占澳大利亚中毒电话的70%);澳大利亚药品福利计划数据10%样本中的药品分配(2012年7月至2016年6月)。参与者5-19岁的人。主要结果指标故意中毒暴露电话的年度趋势,故意中毒中使用的物质,结果5-19岁人群共发生故意中毒33501起,年增长率为8.39%(95%CI 6.08%~ 10.74%,P < 0.01),其中精神药物滥用(抗抑郁药、抗精神病药、苯二氮卓类药物和治疗注意缺陷多动障碍(ADHD)的药物)发生率最高。
Objectives To characterise trends in self-poisoning and psychotropic medicine use in young Australians.Design Population-based retrospective cohort study.Setting Calls taken by the New South Wales and Victorian Poisons Information Centres (2006-2016, accounting for 70% of Australian poisoning calls); medicine dispensings in the 10% sample of Australian Pharmaceutical Benefits Scheme data (July 2012 to June 2016).Participants People aged 5-19 years.Main outcome measures Yearly trends in intentional poisoning exposure calls, substances taken in intentional poisonings, a prevalence of psychotropic use (dispensing of antidepressants, antipsychotics, benzodiazepines and medicines for attention deficit hyperactivity disorder (ADHD)).Results There were 33 501 intentional poisonings in people aged 5-19 years, with an increase of 8.39% per year (95% CI 6.08% to 10.74%, p