Sexual dimorphism in campylobacteriosis
Sexual dimorphism in campylobacteriosis
复制标题
弯曲菌病的性别二态性
DOI：
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复制
发表时间：
2007
影响因子：
4.2
通讯作者：
Jorge E. Galán
中科院分区：
文献类型：
--
作者：
N. Strachan;Robert O. Watson;V. Novik;D. Hofreuter;I. Ogden;Jorge E. Galán
SUMMARY Sexual dimorphism in infectious diseases whereby disease incidence is more prevalent in one gender has been reported repeatedly in the scientific literature. Both behavioural and physiological differences have been suggested as a cause of this gender bias but there is a paucity of data to support either of these viewpoints. Here it is hypothesized that for campylobacteriosis physiological factors play an important role in the higher incidence in males. We demonstrate in the human population (from several countries in three continents) that this bias exists in young children (<1 year) where behavioural differences between genders are likely to be minimal. Further we demonstrate this difference in an animal model where both infection rates and shedding rates of the organism are greater in male mice.
