Biomonitoring in California firefighters: metals and perfluorinated chemicals.

Biomonitoring in California firefighters: metals and perfluorinated chemicals.
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DOI:
10.1097/jom.0000000000000307
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发表时间:
2015-01
影响因子:
3.2
通讯作者:
Das R
Das R
中科院分区:
医学4区
文献类型:
--
作者:
Dobraca D;Israel L;McNeel S;Voss R;Wang M;Gajek R;Park JS;Harwani S;Barley F;She J;Das R

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评估加州消防员血液中选定化学物质的浓度,并与美国代表性人群进行比较。我们报告了101名南加州消防员全血和12种血清全氟化学品中镉、铅、汞和锰的实验室方法和分析结果。消防员的血液金属浓度都类似于或低于国家健康和营养检查调查(NHANES)的值,除了6名参与者的汞浓度(范围:9.79至13.42 μg/L)接近或高于NHANES报告的阈值10 μg/L。与NHANES和其他消防员研究相比,全氟癸酸浓度升高。全氟癸酸浓度在这组消防员比在NHANES成年男性高三倍。消防员可能有不明来源的全氟化学品职业接触。
To assess California firefighters' blood concentrations of selected chemicals and compare with a representative US population. We report laboratory methods and analytic results for cadmium, lead, mercury, and manganese in whole blood and 12 serum perfluorinated chemicals in a sample of 101 Southern California firefighters. Firefighters' blood metal concentrations were all similar to or lower than the National Health and Nutrition Examination Survey (NHANES) values, except for six participants whose mercury concentrations (range: 9.79 to 13.42 μg/L) were close to or higher than the NHANES reporting threshold of 10 μg/L. Perfluorodecanoic acid concentrations were elevated compared with NHANES and other firefighter studies. Perfluorodecanoic acid concentrations were three times higher in this firefighter group than in NHANES adult males. Firefighters may have unidentified sources of occupational exposure to perfluorinated chemicals.