Corticospinal Responses to Sustained Locomotor Exercises: Moving Beyond Single-Joint Studies of Central Fatigue

Corticospinal Responses to Sustained Locomotor Exercises: Moving Beyond Single-Joint Studies of Central Fatigue
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皮质脊髓对持续运动锻炼的反应:超越中枢疲劳的单关节研究

DOI:
10.1007/s40279-013-0020-6
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发表时间:
2013
期刊:
影响因子:
9.8
通讯作者:
T. Carroll
T. Carroll
中科院分区:
医学1区
文献类型:
--
作者:
S. Sidhu;A. Cresswell;T. Carroll

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有大量证据表明,疲劳运动伴随着中枢神经系统的变化,减少了工作肌肉产生的力量。在这里,我们回顾的研究,使用非侵入性神经生理学技术,以表明持续的单关节收缩有能力增加皮质脊髓反应性和减少运动神经元的反应性。我们将这些发现与我们实验室关于持续自行车运动中皮质脊髓反应性的新证据进行了对比。在持续运动和单关节运动过程中,皮质内抑制性中间神经元的反应性似乎也有类似的增加,这可能是由于任何性质的疲劳运动所常见的急性运动反应,例如疲劳代谢物的局部积累。相比之下,皮质脊髓反应性的变化模式是根本不同的两种模式的运动,这可能是由于更大的全身性疲劳运动的反应。
There is substantial evidence that fatiguing exercise is accompanied by changes within the central nervous system that reduce the force that can be produced by working muscles. Here we review studies that used non-invasive neurophysiological techniques to show that sustained single-joint contractions have the capacity to increase corticospinal responsiveness and reduce motoneuronal responsiveness. We contrast these findings with new evidence from our laboratory regarding corticospinal responsiveness during sustained cycling exercise. There seems to be a similar increase in responsiveness of the intracortical inhibitory interneurons during sustained locomotor and single-joint exercise which might be due to acute exercise responses that are common to fatiguing exercise of any nature, such as local accumulation of fatigue metabolites. In contrast, the pattern of changes in corticospinal responsiveness is fundamentally different between the two modes of exercise which might be due to greater systemic fatigue responses to locomotor exercises.
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