THE RELATIONSHIP OF GINGIVAL FLUID LEUKOCYTE ELASTASE ACTIVITY TO GINGIVAL FLUID-FLOW RATE
THE RELATIONSHIP OF GINGIVAL FLUID LEUKOCYTE ELASTASE ACTIVITY TO GINGIVAL FLUID-FLOW RATE
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DOI：
10.1902/jop.1992.63.9.743
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发表时间：
1992-09-01
影响因子：
4.3
通讯作者：
WALTERS, JD
中科院分区：
文献类型：
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作者：
DARANY, DG;BECK, FM;WALTERS, JD
最近的研究表明，组织渗出液中的白细胞弹性蛋白酶活性（EA）是炎症性疾病的指标。我们测定了牙龈液（GF）EA与选择性肽底物和GF流量方面的能力，以检测现有的炎症性牙周病在56人受试者的临床状态的差异进行比较。与健康部位（牙龈指数= 0.1 ~ 3 mm）和轻度牙龈炎部位（GI = 1.2 ~ 5 mm）相比，平均GF EA显著（P
RECENT STUDIES HAVE SUGGESTED that leukocyte elastase activity (EA) in tissue exudates is an indicator of inflammatory disease. We assayed gingival fluid (GF) EA with a selective peptide substrate and compared it to GF flow rate with regard to its ability to detect differences in the clinical status of existing inflammatory periodontal disease in 56 human subjects. Compared to healthy sites (Gingival Index = 0, 1 to 3 mm) and mild gingivitis sites (GI = 1, 2 to 5 mm), mean GF EA was significantly (P