All you wanted to know about spermatogonia but were afraid to ask.
All you wanted to know about spermatogonia but were afraid to ask.
复制标题
DOI：
10.1002/j.1939-4640.2000.tb03408.x
复制
发表时间：
2000-11
影响因子：
--
通讯作者：
D. G. Rooij;L. Russell
中科院分区：
文献类型：
--
作者：
D. G. Rooij;L. Russell
问：如何定义精原细胞？答：精原细胞是指在精子发生开始后，在生精上皮中存在的一种相对不专门的二倍体生殖细胞，它能够进行有丝分裂，最终形成初级精细胞。问：精原细胞是否不止一种？回答：是的，有许多精原细胞类型。不幸的是，尽管最初的命名对受孕的人来说是合乎逻辑的，但更多精原细胞类型的检测使命名法相当混乱。以下问题应该有助于澄清这一点。问题：精原细胞是如何命名的？答：最初只描述了两种类型的精原细胞。第一种是A型精原细胞，在细胞核内不显示异染色质，第二种是B型精原细胞，显示出异染色质(图1)。此后不久，有人发现了一种精原细胞，它含有中等数量的异染色质，被称为中间精原细胞。这些名称是有历史意义的，它们是细胞的广泛类别。当更多世代的精原细胞被发现时，特别是在A型精原细胞中，人们设计了新的名称来对它们进行分类。问题：正是细胞所拥有的异染色质的数量使它们能够被初步归类？
Question: How does one define a spermatogonium? Answer: Spermatogonium is the term given to a relatively unspecialized diploid germ cell present in the seminiferous epithelium after the start of spermatogenesis that is able to carry out mitotic divisions, ultimately giving rise to primary spermatocytes.Question: Is there more than 1 type of spermatogonia?Answer: Yes, there are a number of spermatogonial types. Unfortunately, although the first assigned names were logical to those who conceived of them, the detection of more spermatogonial cell types has made the nomenclature rather confusing. The following questions should help clarify this.Question: How are spermatogonia named? Answer: In the beginning only 2 types of spermatogonia were described. The first, type A spermatogonium, did not display heterochromatin in the nucleus and the second, type B spermatogonium, did display heterochromatin (Figure 1). Shortly thereafter, someone found a type of spermatogonium that had an intermediate amount of heterochromatin, which was termed intermediate (In) spermatogonium. These names are historical, and they are broad categories of cells. When more generations of spermatogonia were discovered, especially among the type A category, new names were devised to categorize them.Question: It was the amount of heterochromatin that cells possessed that allowed them to be initially categorized?