Systemic and vaginal biomechanical properties of women with normal vaginal support and pelvic organ prolapse
Systemic and vaginal biomechanical properties of women with normal vaginal support and pelvic organ prolapse
复制标题
DOI：
10.1016/j.ajog.2007.03.040
复制
发表时间：
2007-08-01
影响因子：
9.8
通讯作者：
Heit, Michael H.
中科院分区：
文献类型：
--
作者：
Epstein, Lee B.;Graham, Carol A.;Heit, Michael H.
目的：本研究的目的是比较生物力学性能的阴道和全身皮肤的妇女和没有盆腔器官prolongation.Study设计：在这个横断面研究，25名妇女盆腔器官脱垂和23名年龄匹配的妇女与正常的盆腔支持被招募从办公室设置。A Cutometer MPA 580和DermaLab皮肤探针被用来测量全身生物力学参数和1.5 mm偏移DermaLab皮肤探针被用于阴道生物力学measurements.RESULTS：有两组之间的基线人口统计学，产科，或妇科信息没有显着差异。两组之间的全身生物力学参数无显著差异。盆腔器官脱垂的女性比盆腔支撑正常的女性阴道皮肤更易伸展（初始硬度指数7.3 vs 10.9 kPa，最终硬度指数5.9 vs 10.7 kPa;所有P值均小于0.01）。此外，阴道伸展性与盆腔器官脱垂的量化阶段在一个线性fashion.CONCLUSION：我们的研究结果表明，局部，而不是全身，皮肤生物力学特性的改变与盆腔器官脱垂。
OBJECTIVE: The objective of the study was to compare the biomechanical properties of vaginal and systemic skin in women with and without pelvic organ prolapse.STUDY DESIGN: In this cross- sectional study, 25 women with pelvic organ prolapse and 23 age- matched women with normal pelvic support were recruited from an office setting. A Cutometer MPA 580 and DermaLab skin probe were used to measure systemic biomechanical parameters and a 1.5 mm offset DermaLab skin probe was used for vaginal biomechanical measurements.RESULTS: There were no significant differences in the baseline demographic, obstetrical, or gynecologic information between the 2 groups. There were no significant differences in the systemic biomechanical parameters between the 2 groups. Women with pelvic organ prolapse had significantly more extensible vaginal skin than women with normal pelvic support (initial stiffness index 7.3 vs 10.9 kpa, final stiffness index 5.9 vs 10.7 kpa; all P values less than .01). Furthermore, vaginal extensibility was related to pelvic organ prolapse quantification stage in a linear fashion.CONCLUSION: Our findings suggest that local, rather than systemic, alterations in biomechanical skin properties are associated with pelvic organ prolapse.